{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T17:18:15Z","timestamp":1793985495946,"version":"4.8.0"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2011,10,4]],"date-time":"2011-10-04T00:00:00Z","timestamp":1317686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Long\u2010term success of osteointegrated dental implants requires sufficient volume of healthy bone at the recipient sites. However, this is frequently lacking as a result of trauma, tooth loss, or infection. Onlay autografting is amongst the most predictable techniques for craniofacial vertical bone augmentation, however, complications related to donor site morbidity are common and alternatives to onlay autografts are desirable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To develop and evaluate a new synthetic onlay block for vertical bone augmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Sixteen synthetic monetite monolithic discs\u2010shaped blocks were prepared using a 3D\u2010printing technique. The blocks were computer\u2010designed, and had a diameter of 9.0\u00a0mm, a thickness of either 4.0\u00a0mm (n\u00a0=\u00a08) or 3.0\u00a0mm (n\u00a0=\u00a08) and one 0.5\u2010mm wide central hole that enabled their surgical fixation with osteosynthesis screws. The blocks were randomly allocated to each side of the calvaria (right or left) of eight New Zealand rabbits and fixed with screws to achieve vertical bone augmentation. Eight weeks after the surgical intervention, the animals were sacrificed and the calvaria were retrieved for histological analysis. The following parameters were analysed: the interaction between the graft and the original bone surface, the amount of bone ingrowth within the graft and the gain in bone height achieved by the procedure. Wilcoxon <jats:italic>t<\/jats:italic>\u2010test was used to evaluate significant differences between the two types of monetite bone block grafts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The blocks were easy to handle and no damage or fracture was registered while being screw\u2010fixated to the calvarial bone. As a result, the surgical procedure was easy and quick. After a healing of 8\u00a0weeks, the synthetic blocks were strongly fused to the calvarial bone surface. Upon histological observation, the monetite blocks appeared to be infiltrated by newly formed bone, without histological signs of necrosis, osteolysis or foreign body reaction. Histomorphometry revealed that bone augmentation occurred within and over the monetite block. The 4.0\u2010 and 3.0\u2010mm high blocks were filled with newly formed bone with 35% and 41% of their respective volumes. These observations indicated that craniofacial bone augmentations of at least 4\u00a0mm could be achieved with synthetic monetite blocks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Within the limits of our study, this novel material may be able to eliminate the need for autologous bone transplantation for the augmentation of large vertical bone defects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-051x.2011.01787.x","type":"journal-article","created":{"date-parts":[[2011,10,4]],"date-time":"2011-10-04T07:23:53Z","timestamp":1317713033000},"page":"1147-1153","source":"Crossref","is-referenced-by-count":64,"title":["Vertical bone augmentation with 3D\u2010synthetic monetite blocks in the rabbit calvaria"],"prefix":"10.1111","volume":"38","author":[{"given":"Jes\u00fas","family":"Torres","sequence":"first","affiliation":[{"name":"Department of Stomatology Anatomy and Embriology Universidad Rey Juan Carlos  Alcorc\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faleh","family":"Tamimi","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hamdan","family":"Alkhraisat","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy Universidad Complutense  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Prados\u2010Frutos","sequence":"additional","affiliation":[{"name":"Department of Stomatology Anatomy and Embriology Universidad Rey Juan Carlos  Alcorc\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad","family":"Rastikerdar","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Gbureck","sequence":"additional","affiliation":[{"name":"Department for Functional Materials in Medicine and Dentistry University of W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jake E.","family":"Barralet","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"L\u00f3pez\u2010Cabarcos","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy Universidad Complutense  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,10,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2009.06.010"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.291213.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.6.1015"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(83)90318-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1997.080206.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.140201.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01351.x"},{"key":"e_1_2_6_9_1","first-page":"167","article-title":"The efficacy of horizontal and vertical bone augmentation procedures for dental implants \u2013 a Cochrane systematic review","volume":"2","author":"Esposito M.","year":"2010","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_6_10_1","first-page":"7","article-title":"Vertical bone augmentation versus 7\u2010mm\u2010long implants in posterior atrophic mandibles. 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