{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:20:29Z","timestamp":1789050029244,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,10,24]],"date-time":"2011-10-24T00:00:00Z","timestamp":1319414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the associations of oral hygiene and periodontal health with chronic obstructive pulmonary disease (<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>) exacerbations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>In total, 392 <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients were divided into frequent and infrequent exacerbation (\u22652 times and &lt;2 times in last 12\u00a0months) groups. Their lung function and periodontal status were examined. Information on oral hygiene behaviours was obtained by interview.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the univariate analysis, fewer remaining teeth, high plaque index (<jats:styled-content style=\"fixed-case\">PLI<\/jats:styled-content>) scores, low tooth brushing times, and low regular supra\u2010gingival scaling were significantly associated with <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> exacerbations (all <jats:italic>p\u2010<\/jats:italic>values &lt;0.05). After adjustment for age, gender, body mass index, <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> severity and dyspnoea severity, the associations with fewer remaining teeth (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.02), high <jats:styled-content style=\"fixed-case\">PLI<\/jats:styled-content> scores (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.02) and low tooth brushing times (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.008) remained statistically significant. When stratified by smoking, fewer remaining teeth (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a02.05, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.04\u20134.02) and low tooth brushing times (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a04.90, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.26\u201319.1) among past smokers and high <jats:styled-content style=\"fixed-case\">PLI<\/jats:styled-content> scores (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a03.43, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.19\u20139.94) among never smokers were significantly associated with <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> exacerbations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fewer remaining teeth, high <jats:styled-content style=\"fixed-case\">PLI<\/jats:styled-content> scores, and low tooth brushing times are significant correlates of <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> exacerbations, indicating that improving periodontal health and oral hygiene may be a potentially preventive strategy against <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> exacerbations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-051x.2011.01808.x","type":"journal-article","created":{"date-parts":[[2011,10,25]],"date-time":"2011-10-25T00:45:03Z","timestamp":1319503503000},"page":"45-52","source":"Crossref","is-referenced-by-count":83,"title":["Oral hygiene, periodontal health and chronic obstructive pulmonary disease exacerbations"],"prefix":"10.1111","volume":"39","author":[{"given":"Zhiqiang","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Stomatology Beijing ChaoYang Hospital affiliated to Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Stomatology Beijing Hai Dian Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Stomatology Beijing ChaoYang Hospital affiliated to Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Stomatology Beijing ChaoYang Hospital affiliated to Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangqiong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Stomatology Beijing ChaoYang Hospital affiliated to Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqing","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine Brigham &amp; 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