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Within 5\u00a0days after labour, clinical periodontal parameters and <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic>,<jats:italic> Porphyromonas gingivalis<\/jats:italic> and <jats:italic>Prevotella intermedia<\/jats:italic> in subgingival plaque were evaluated. Maternal serum IgG antibody specific for each bacteria was determined by enzyme\u2010linked immunosorbent assay. Multivariate logistic regression analysis was used to control for confounders (maternal age, body mass index before pregnancy, parity, and smoking).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighteen women were affected with preeclampsia. The number of <jats:italic>A.actinomycetemcomitans<\/jats:italic> was shown to be significantly associated with preeclampsia in the logistic regression model (odds ratio; 1.7, 95% confidence interval; 1.1\u20132.7). There were statistically significant differences between the preeclamptic and control groups in body mass index before pregnancy, pre\u2010term birth and low birthweight (respectively, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.014, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010 and <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.0001). We found no statistically significant association between preeclampsia and periodontal clinical parameters or the presence of periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In systemically healthy pregnant women, our findings suggested that the levels of maternal subgingival <jats:italic>A. actinomycetemcomitans<\/jats:italic> DNA were elevated in preeclamptic women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-051x.2011.01845.x","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T11:00:04Z","timestamp":1326193204000},"page":"229-238","source":"Crossref","is-referenced-by-count":14,"title":["The association of <i>Aggregatibacter actinomycetemcomitans<\/i> with preeclampsia in a subset of Japanese pregnant women"],"prefix":"10.1111","volume":"39","author":[{"given":"Emi","family":"Hirano","sequence":"first","affiliation":[{"name":"Division of Periodontology Department of Oral Biological Science Graduate 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