{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T20:09:00Z","timestamp":1788206940461,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2012,7]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Limited evidence exists on the efficacy of regenerative treatment of peri\u2010implantitis.<\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n Subjects receiving antibiotics and surgical debridement were randomly assigned to placement of autogenous bone (\n AB<\/jats:styled-content>\n ) or bovine\u2010derived xenograft (\n BDX<\/jats:styled-content>\n ) and with placement of a collagen membrane. The primary outcome was evidence of radiographic bone fill and the secondary outcomes included reductions of probing depth (\n PD<\/jats:styled-content>\n ) bleeding on probing (\n BOP<\/jats:styled-content>\n ) and suppuration.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Twenty\u2010two subjects were included in the\n AB<\/jats:styled-content>\n and 23 subjects in the\n BDX<\/jats:styled-content>\n group. Statistical analysis failed to demonstrate differences for 38\/39 variables assessed at baseline. At 12\u00a0months, significant better results were obtained in the\n BDX<\/jats:styled-content>\n group for bone levels (\n p<\/jats:italic>\n \u00a0<\u00a00.001),\n BOP<\/jats:styled-content>\n (\n p<\/jats:italic>\n \u00a0=\u00a00.004),\n PI<\/jats:styled-content>\n (\n p<\/jats:italic>\n \u00a0=\u00a00.003) and suppuration (\n p<\/jats:italic>\n \u00a0<\u00a00.01). When adjusting for number of implants treated per subject, a successful treatment outcome\n PD<\/jats:styled-content>\n \u00a0\u2264\u00a05.0\u00a0mm, no pus, no bone loss and\n BOP<\/jats:styled-content>\n at 1\/4 or less sites the likelihood of defect fill was higher in the\n BDX<\/jats:styled-content>\n group (\n LR<\/jats:styled-content>\n : 3.2, 95%\n CI<\/jats:styled-content>\n : 1.0\u201310.6,\n p<\/jats:italic>\n \u00a0<\u00a00.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Bovine xenograft provided more radiographic bone fill than AB. The success for both surgical regenerative procedures was limited. Decreases in\n PD<\/jats:styled-content>\n ,\n BOP<\/jats:styled-content>\n , and suppuration were observed.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/j.1600-051x.2012.01880.x","type":"journal-article","created":{"date-parts":[[2012,3,24]],"date-time":"2012-03-24T04:40:37Z","timestamp":1332564037000},"page":"666-673","source":"Crossref","is-referenced-by-count":93,"title":["A single\u2010centre randomized controlled clinical trial on the adjunct treatment of intra\u2010bony defects with autogenous bone or a xenograft: results after 12\u00a0months"],"prefix":"10.1111","volume":"39","author":[{"given":"Ahmad","family":"Aghazadeh","sequence":"first","affiliation":[{"name":"Uppsala K\u00e4kkirurgiska Centrum Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Rutger Persson","sequence":"additional","affiliation":[{"name":"Department of Oral Sciences Kristianstad University Kristianstad Kristianstad Sweden"},{"name":"Departments of Periodontics and Oral Medicine University of Washington Seattle WA"},{"name":"Department of Periodontology University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Renvert","sequence":"additional","affiliation":[{"name":"Department of Oral Sciences Kristianstad University Kristianstad Kristianstad Sweden"},{"name":"School of Dental Sciences Trinity Collage Dublin Ireland"},{"name":"Blekinge Institute of Technology Karlskrona Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"125","article-title":"Treatment of peri\u2010implantitis defects with autogenous bone grafts: six\u2010month to 3\u2010year results of a prospective study in 17 patients","volume":"15","author":"Behneke A.","year":"2000","journal-title":"International Journal of Oral Maxillofacial 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