{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T12:02:34Z","timestamp":1704283354999},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,5,22]],"date-time":"2012-05-22T00:00:00Z","timestamp":1337644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title><jats:italic>Abstract<\/jats:italic><\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to evaluate the utility of a simple colorimetric chair side test detecting amines in saliva as an adjunct test in the oral malodour diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Non\u2010stimulated saliva samples were collected from 100 volunteers with different degrees of oral malodour. The amount of amines detected by the test was estimated clinically (colorimetric test), confirmed semi quantitatively in the laboratory (standard addition method) and consequently compared with (<jats:italic>i<\/jats:italic>) the organoleptic score (OLS); (<jats:italic>ii<\/jats:italic>) the volatile sulphur compounds (VSCs) levels (OralChroma<jats:sup>\u2122<\/jats:sup>) and (<jats:italic>iii<\/jats:italic>) the amount of amines detected by means of gas chromatography \u2013 mass spectroscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The chair side test correlated well (Spearman correlation coefficient: 0.46\u20130.77), with the OLS, the level of VSCs, and the amines determined by using gas chromatography \u2013 mass spectroscopy. The results of the new test for patients with and without oral malodour were significantly different (Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.0001). The sensitivity, specificity, and positive and negative predictive value of this chair side test were similar to those of the VSCs evaluations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results support the \u201cfit for purpose\u201d of the new chair side test as adjunctive diagnostic tool for oral malodour.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-051x.2012.01901.x","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T15:15:21Z","timestamp":1335539721000},"page":"645-650","source":"Crossref","is-referenced-by-count":8,"title":["Clinical utility of a novel colorimetric chair side test for oral malodour"],"prefix":"10.1111","volume":"39","author":[{"given":"Jesica","family":"Dadamio","sequence":"first","affiliation":[{"name":"Department of Periodontology Catholic University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Van Tornout","sequence":"additional","affiliation":[{"name":"Department of Periodontology Catholic University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederique","family":"Vancauwenberghe","sequence":"additional","affiliation":[{"name":"Department of Periodontology Catholic University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Federico","sequence":"additional","affiliation":[{"name":"Department of Biology University of Roma Tre  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christel","family":"Dekeyser","sequence":"additional","affiliation":[{"name":"Department of Periodontology Catholic University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Quirynen","sequence":"additional","affiliation":[{"name":"Department of Periodontology Catholic University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,5,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(03)00015-3"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1088\/1752-7155\/5\/4\/046003"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6505700"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345940730060701"},{"key":"e_1_2_5_6_1","first-page":"149","volume-title":"Bad Breath: Research Perspectives","author":"Goldberg S.","year":"1995"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910408300116"},{"key":"e_1_2_5_8_1","volume-title":"Quantitative Chemical Analysis","author":"Harris D. 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