{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T04:43:05Z","timestamp":1794631385428,"version":"4.9.1"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2012,5,28]],"date-time":"2012-05-28T00:00:00Z","timestamp":1338163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this randomized clinical trial (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>) was to evaluate the adjunctive benefit of Connective Tissue Graft (<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>) to Coronally Advanced Flap (<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>) for the treatment of gingival recession associated with inter\u2010dental clinical attachment loss equal or smaller to the buccal attachment loss (<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>A total of 29 patients with one recession were enrolled; 15 patients were randomly assigned to <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> while 14 to <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> alone. Measurements were performed by a blind and calibrated examiner. Outcome measures included complete root coverage (<jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content>), recession reduction (RecRed), Root coverage Esthetic Score (<jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content>), intra\u2010operative and post\u2010operative morbidity, and root sensitivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 6\u00a0months, <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> resulted in better outcomes in terms of <jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content> (adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a015.51, <jats:italic>p\u00a0<\/jats:italic>=\u00a00.0325) than <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> alone. <jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content> was observed in &gt;80% of the cases treated with <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> when the baseline amount of inter\u2010dental <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> was \u22643\u00a0mm. No difference was detected in term of RecRed. <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> was associated with longer surgical\u2010time (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.0001), higher number of days with post\u2010operative morbidity (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.0222) and the need for a greater number of analgesics (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.0178) than <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> alone. No difference for final <jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content> score was detected (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.1612).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both treatments can provide <jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content> in single gingival recession with inter\u2010dental <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> loss. The application of <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> under <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> resulted in predictable <jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content> when inter\u2010dental <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> was \u22643\u00a0mm.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-051x.2012.01903.x","type":"journal-article","created":{"date-parts":[[2012,4,20]],"date-time":"2012-04-20T13:22:27Z","timestamp":1334928147000},"page":"760-768","source":"Crossref","is-referenced-by-count":85,"title":["Coronally advanced flap with and without connective tissue graft for the treatment of single maxillary gingival recession with loss of inter\u2010dental attachment. A randomized controlled clinical trial"],"prefix":"10.1111","volume":"39","author":[{"given":"Francesco","family":"Cairo","sequence":"first","affiliation":[{"name":"Department of Periodontology and Implant Dentistry Tuscan School of Dental Medicine Florence\u2010Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Cortellini","sequence":"additional","affiliation":[{"name":"Accademia Toscana di Ricerca Odontostomatologia (ATRO) Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Tonetti","sequence":"additional","affiliation":[{"name":"European Research Group on Periodontology (ERGOPERIO) Berne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Nieri","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Dentistry Tuscan School of Dental Medicine Florence\u2010Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Mervelt","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Dentistry Tuscan School of Dental Medicine Florence\u2010Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Cincinelli","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Dentistry Tuscan School of Dental Medicine Florence\u2010Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanpaolo","family":"Pini\u2010Prato","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Implant Dentistry Tuscan School of Dental Medicine Florence\u2010Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01492.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100278"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01732.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080565"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2008.05.007"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2009.0158"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.110382"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.5.741"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01346.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(90)90005-M"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.4.470"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.52.463"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01348.x"},{"key":"e_1_2_5_16_1","first-page":"297","article-title":"The single\u2010incision palatal harvest technique: a strategy for esthetics and patient comfort","volume":"20","author":"Lorenzana E. R.","year":"2000","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_5_17_1","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller P. D.","year":"1985","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1989.tb02146.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.5.713"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01655.x"},{"key":"e_1_2_5_21_1","first-page":"603","article-title":"Esthetic evaluation of root coverage outcomes: a case series study","volume":"31","author":"Pini\u2010Prato G.","year":"2011","journal-title":"International Journal Periodontics Restorative Dentistry"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.6.760"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-051X.2012.01903.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-051X.2012.01903.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T13:07:47Z","timestamp":1700572067000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-051X.2012.01903.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,28]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1111\/j.1600-051X.2012.01903.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-051x.2012.01903.x","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,28]]}}}