{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:03:47Z","timestamp":1787015027775,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T00:00:00Z","timestamp":1270598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comm Dent Oral Epid"],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:p>Feldens CA, Giugliani ERJ, Duncan BB, Drachler ML, V\u00edtolo MR. Long\u2010term effectiveness of a nutritional program in reducing early childhood caries: a randomized trial. Community Dent Oral Epidemiol 2010; 38: 324\u2013332. \u00a9 2010 John Wiley &amp; Sons A\/S<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Abstract\u2002\u2013\u2002<\/jats:bold>\n                    <jats:bold>Objectives:\u2002<\/jats:bold>\n                    To investigate the effectiveness of home visits advising mothers about healthy feeding practices during the first year of life on the occurrence of early childhood caries and severe early childhood caries at 4 years of age.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:\u2002<\/jats:bold>\n                    We conducted a parallel randomized trial of mothers of single, full\u2010term children with birthweight \u2265 2500g in S\u00e3o Leopoldo, Brazil. The intervention group received monthly advice up to 6 months and then at 8, 10 and 12 months by undergraduate nutrition students, based on the ``Ten Steps for Healthy Feeding'', a Brazilian national health policy for primary care based on World Health Organization guidelines. The primary outcome was the occurrence of early childhood caries at age four. Secondary outcomes included the occurrence of severe early childhood caries and the number of affected teeth: decayed (white spots and cavities), missing and filled teeth (d\n                    <jats:sub>1+<\/jats:sub>\n                    mft). Blinded observers ascertained feeding habits in the home and one blinded dentist performed dental examinations in a municipal clinic. This study is registered with ClinicalTrials.gov, number NCT00629629.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:\u2002<\/jats:bold>\n                    Of 500 mother\u2010child pairs (200 intervention, 300 control) enrolled, 340 (141 intervention, 199 control) completed 4 year follow\u2010up. As 138 (69.3%) controls but only 76 (53.9%) intervention children had early childhood caries, home counseling reduced incidence by 22% (RR 0.78; 95% CI 0.65\u20100.93). Severe early childhood caries incidence was reduced by 32% (RR 0.68; 95% CI 050\u20100.92). The mean number of affected teeth was lower for the intervention group (3.25) compared with the control group (4.15) (Mann Whitney U\u2010test; p=0.023). No adverse effects were noted.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:\u2002<\/jats:bold>\n                    Home nutritional advice during the first year of life decreases caries incidence and severity at four years of age in a low income community.\n                  <\/jats:p>","DOI":"10.1111\/j.1600-0528.2010.00540.x","type":"journal-article","created":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T05:55:08Z","timestamp":1270619708000},"page":"324-332","source":"Crossref","is-referenced-by-count":112,"title":["Long\u2010term effectiveness of a nutritional program in reducing early childhood caries: a randomized trial"],"prefix":"10.1111","volume":"38","author":[{"given":"Carlos Alberto","family":"Feldens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa Regina Justo","family":"Giugliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce Bartholow","family":"Duncan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria de Lourdes","family":"Drachler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia Regina","family":"V\u00edtolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,7,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2006.00352.x"},{"issue":"1","key":"e_1_2_6_3_2","first-page":"121","article-title":"International comarisons of health inequalities in childhood dental caries","volume":"21","author":"Pine CM","year":"2004","journal-title":"Community Dent Health"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2008.00448.x"},{"key":"e_1_2_6_5_2","unstructured":"Brasil MS\/SAS. Projeto SB Brasil 2003.Condi\u00e7\u00f5es de sa\u00fade bucal da popula\u00e7\u00e3o brasileira 2002\u20132003 \u2013 Resultados principais. Bras\u00edlia 2004."},{"key":"e_1_2_6_6_2","first-page":"328","article-title":"Determinants of health in children and the problem of early childhood caries","volume":"25","author":"Ismail AI","year":"2003","journal-title":"Pediatr Dent"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2006.00246.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2007.00385.x"},{"key":"e_1_2_6_9_2","first-page":"711","article-title":"Strategies and approaches in oral disease prevention and health promotion","volume":"83","author":"Watt RG","year":"2005","journal-title":"Bull World Health Organ"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2005000500028"},{"key":"e_1_2_6_11_2","first-page":"86","article-title":"Developing explanatory models of health inequalities in childhood dental caries","volume":"21","author":"Pine CM","year":"2004","journal-title":"Community Dent Health"},{"key":"e_1_2_6_12_2","volume-title":"Global strategy for the prevention and control of non\u2010communicable diseases","author":"World Health Organization","year":"2000"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0528.2000.028006399.x"},{"key":"e_1_2_6_14_2","volume-title":"Ten steps for healthy feeding","author":"Brazil. Health Ministry"},{"key":"e_1_2_6_15_2","volume-title":"Ten steps for healthy feeding","author":"Brazil. Health Ministry"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2005000500018"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2008.07.008"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2006.00337.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2007.00831.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/82.4.721"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-7325.1999.tb03268.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198806303182605"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2004.00197.x"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509334043"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/0022034508328629"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2008.00447.x"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(02)90349-4"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1875-595X.2004.tb00250.x"},{"key":"e_1_2_6_29_2","first-page":"253","article-title":"The process and outcome of a programme for preventing early childhood caries in Thailand","volume":"22","author":"Vachirarojpisan T","year":"2005","journal-title":"Community Dent Health"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1159\/000108596"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2006.0291"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2007.00414.x"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03262553"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2008.00430.x"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-7325.1999.tb03267.x"},{"key":"e_1_2_6_36_2","volume-title":"Clinical epidemiology: the essentials","author":"Fletcher RH","year":"2005"},{"key":"e_1_2_6_37_2","first-page":"644","article-title":"Oral health, general health and quality of life","volume":"83","author":"Sheiham A","year":"2005","journal-title":"Bull World Health Organ"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2005.038323"},{"key":"e_1_2_6_39_2","first-page":"131","article-title":"A randomised controlled trial of the effectiveness of providing free fluoride toothpaste from the age of 12\u2003months on reducing caries in 5\u20106\u2010year old children","volume":"19","author":"Davies GM","year":"2002","journal-title":"Community Dent Health"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1177\/154405910608500211"},{"key":"e_1_2_6_41_2","doi-asserted-by":"publisher","DOI":"10.1159\/000104800"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2008.00427.x"},{"key":"e_1_2_6_43_2","doi-asserted-by":"publisher","DOI":"10.1159\/000209343"}],"container-title":["Community Dentistry and Oral Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0528.2010.00540.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0528.2010.00540.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T04:07:37Z","timestamp":1698725257000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0528.2010.00540.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,6]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["10.1111\/j.1600-0528.2010.00540.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0528.2010.00540.x","archive":["Portico"],"relation":{},"ISSN":["0301-5661","1600-0528"],"issn-type":[{"value":"0301-5661","type":"print"},{"value":"1600-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,6]]}}}