{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T11:57:54Z","timestamp":1772020674326,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T00:00:00Z","timestamp":1171411200000},"content-version":"vor","delay-in-days":3180,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[1998,6]]},"abstract":"<jats:p>This study compares the cutaneous reactivity between the hand and the back for 7 female patients with active hand eczema, who were found to be nickel\u2010sensitive on routine patch testing with the European standard series. Patients were patch tested to a dilution series of nickel sulfate on the back in order to determine the threshold concentration for elicitation of allergic contact dermatitis, and based upon this result a lower concentration of nickel was then used for patch tests on the hand. We found that in the majority of patients (6\/7) the cutaneous responsiveness of the hand was not increased compared with that of the back. However, the hand of 1 patient was more sensitive to nickel and patch testing was accompanied with a flare of her eczema, which suggests that cutaneous hyperreactivity may be important in individual patients with hand eczema.<\/jats:p>","DOI":"10.1111\/j.1600-0536.1998.tb05765.x","type":"journal-article","created":{"date-parts":[[2007,2,15]],"date-time":"2007-02-15T04:54:44Z","timestamp":1171515284000},"page":"316-318","source":"Crossref","is-referenced-by-count":23,"title":["Cutaneous reactivity of the hands in nickel\u2010sensitive patients with hand eczema"],"prefix":"10.1111","volume":"38","author":[{"given":"C. C.","family":"Banfield","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. A.","family":"Basketter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"Powell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,14]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"418","volume-title":"Textbook of contact dermatitis","author":"Andersen KE","year":"1992"},{"key":"e_1_2_1_3_2","first-page":"133","volume-title":"Nickel and the skin: immunology and toxicology","author":"Wilkinson DS","year":"1989"},{"key":"e_1_2_1_4_2","first-page":"271","volume-title":"Practical con\u2010tact dermatitis. A handbook for the practitioner","author":"Guin JD.","year":"1995"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1992.tb00300.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1983.tb04470.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1993.tb03371.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1995.tb00802.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1997.tb00312.x"},{"key":"e_1_2_1_10_2","first-page":"52","volume-title":"Practical contact dermatitis. A handbook for the practitioner","author":"Bruze M.","year":"1995"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1991.tb01663.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb00693.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0536.1998.tb05765.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0536.1998.tb05765.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T14:32:49Z","timestamp":1696170769000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0536.1998.tb05765.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["10.1111\/j.1600-0536.1998.tb05765.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0536.1998.tb05765.x","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}