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CS\u2010allergic patient's sensitization\/tolerance profile and define the potential replacement agents that can still be tolerated.<\/jats:p><jats:p><jats:bold>Methods.<\/jats:bold> Analysis of the patch test results and concomitant (cross\u2010) reaction patterns obtained with 315 corticosteroid\u2010allergic patients, as well as molecular modelling of molecules.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> Proposal of a simplified classification of corticosteroids as to their allergenic properties into 3 groups, determination of two patient profiles according to steric and electrostatic properties of the molecules.<\/jats:p><jats:p><jats:bold>Conclusion.<\/jats:bold> Practical information to the medical profession in order to detect and manage such reactions is 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