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This review offers important information on the requirements for correct validation of screening tests, and concludes that, in its present form, the hair dye self\u2010test has severe limitations: (i) it is not a screening test but a diagnostic test; (ii) it has not been validated according to basic criteria defined by scientists; (iii) it has been evaluated in the wrong population group; (iv) skin reactions have been read by dermatologists and not by the targeted group (consumers and hairdressers); (v) hair dyes contain strong and extreme sensitizers that are left on the skin in high concentrations, potentially resulting in active sensitization; and (vi) recommendations and instructions on how to perform the hair dye self\u2010test vary greatly even among products from the same company, again suggesting that the basis for safe use of the test has not been determined. If the use of a hair dye self\u2010test to predict contact sensitization becomes widespread, there is severe risk that a tool has been marketed that may cause morbidity in European consumers.<\/jats:p>","DOI":"10.1111\/j.1600-0536.2012.02078.x","type":"journal-article","created":{"date-parts":[[2012,5,9]],"date-time":"2012-05-09T07:15:17Z","timestamp":1336547717000},"page":"300-311","source":"Crossref","is-referenced-by-count":27,"title":["Self\u2010testing for contact sensitization to hair dyes \u2013 scientific considerations and clinical concerns of an industry\u2010led screening programme"],"prefix":"10.1111","volume":"66","author":[{"given":"Jacob 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