{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T05:41:20Z","timestamp":1697002880787},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> Dermatofibromas are common benign cutaneous fibrohistiocytic neoplasms, whereas melanomas are potentially aggressive malignancies. Differentiating these two entities can occasionally be difficult.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> We report the case of a 56\u2010year\u2010old female presenting with a firm pink papule on the left thigh.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Histopathology revealed atypical melanocytes in the epidermis and papillary dermis with numerous mitotic figures and intraepidermal pagetoid spread. Within the dermis was a poorly demarcated collection of epithelioid and spindled cells with intermixed keloidal collagen. The atypical melanocytes stained for MART\u20101 and S\u2010100, whereas the underlying fibrohistiocytic tumor took up factor XIIIa immunostain, confirming the diagnosis of invasive malignant melanoma occurring in association with a dermatofibroma.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> This case emphasizes the role of immunohistochemical stains in correctly diagnosing melanocytic and histiocytic neoplasms.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2006.00618.x","type":"journal-article","created":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T15:27:58Z","timestamp":1152631678000},"page":"420-422","source":"Crossref","is-referenced-by-count":7,"title":["Melanoma associated with a dermatofibroma"],"prefix":"10.1111","volume":"34","author":[{"given":"Bradley T.","family":"Kovach","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan S.","family":"Boyd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800384"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1996.tb02711.x"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1992.tb01667.x"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1990.tb00117.x"},{"issue":"5","key":"e_1_2_4_6_2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1001\/archderm.1975.01630170047005","article-title":"Basal cell carcinomas and basal cell carcinoma\u2010like changes overlying dermatofibromas","volume":"111","author":"Goette DK","year":"1975","journal-title":"Arch Dermatol"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199706000-00012"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200104000-00002"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199702000-00007"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03770.x"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199406000-00005"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199907000-00006"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199906000-00003"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.SMJ.0000055103.97445.AB"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247393"},{"issue":"4","key":"e_1_2_4_16_2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2340\/000155557283285","article-title":"Amelanotic acral melanoma masquerading as fibrous histiocytic tumours. Three case reports","volume":"73","author":"Hara M","year":"1993","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199902000-00001"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200402000-00018"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200302000-00001"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2004.00173.x"},{"key":"e_1_2_4_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200006000-00005"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0560.2006.00618.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0560.2006.00618.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T21:51:52Z","timestamp":1696974712000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0560.2006.00618.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,11]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["10.1111\/j.1600-0560.2006.00618.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0560.2006.00618.x","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,11]]}}}