{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T21:13:25Z","timestamp":1723497205816},"reference-count":4,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,8,17]],"date-time":"2007-08-17T00:00:00Z","timestamp":1187308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> The Congo red staining properties of <jats:italic>Candida<\/jats:italic> organisms in clinical tissue specimens have not, to the best of our knowledge, previously been reported. The objective of this study was to determine if the Congo red staining characteristics of <jats:italic>Candida<\/jats:italic> vs. <jats:italic>Histoplasma<\/jats:italic>, <jats:italic>Pityrosporum<\/jats:italic> and <jats:italic>Blastomyces<\/jats:italic> could provide useful diagnostic information. Archival tissue specimens that contained <jats:italic>Histoplasma<\/jats:italic>, <jats:italic>Pityrosporum<\/jats:italic>, <jats:italic>Candida<\/jats:italic> and <jats:italic>Blastomyces<\/jats:italic> were stained with Congo red. The results of the Congo red staining were compared with the diagnoses which were originally rendered on the tissue. Nine out of nine cases (100%) of <jats:italic>Blastomyces<\/jats:italic> were Gomori methenamine silver (GMS) positive and Congo red positive, seven out of seven cases (100%) of <jats:italic>Histoplasma<\/jats:italic> were GMS positive and Congo red negative, and eight out of eight cases (100%) that had <jats:italic>Pityrosporum<\/jats:italic> were GMS positive and Congo red positive; these results corroborate with previously described staining patterns for each respective organism. Nine out of nine cases (100%) that had <jats:italic>Candida<\/jats:italic> were GMS positive and Congo red negative. Differential Congo red staining of <jats:italic>Candida<\/jats:italic> organisms can provide a rapid and accurate method of diagnosis in tissue specimens vs. <jats:italic>Blastomyces<\/jats:italic> and <jats:italic>Pityrosporum<\/jats:italic>, but not vs. <jats:italic>Histoplasma<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2007.00769.x","type":"journal-article","created":{"date-parts":[[2007,8,18]],"date-time":"2007-08-18T00:06:44Z","timestamp":1187395604000},"page":"27-30","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of the use of Congo red staining in the differential diagnosis of <i>Candida<\/i> vs. various other yeast\u2010form fungal organisms"],"prefix":"10.1111","volume":"35","author":[{"given":"Glen K.","family":"Axelson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamar","family":"Giorgadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George A.","family":"Youngberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,12,11]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1529","article-title":"Narrow\u2010spectrum histochemical staining of fungi","volume":"2003","author":"Youngberg GA","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_6_3_2","first-page":"80","article-title":"Combined histochemical stains in the differential diagnosis of Cryptococcus neoformans","volume":"6","author":"Lazcano O","year":"1993","journal-title":"Mod Pathol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2006.00537.x"},{"key":"e_1_2_6_5_2","first-page":"440","article-title":"Acid\u2010fastness of fungi in blastomycosis and histoplasmosis","volume":"106","author":"Wages DS","year":"1982","journal-title":"Arch Pathol Lab Med"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0560.2007.00769.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0560.2007.00769.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T19:57:08Z","timestamp":1697054228000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0560.2007.00769.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12,11]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1111\/j.1600-0560.2007.00769.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0560.2007.00769.x","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12,11]]}}}