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A 50\u2010year\u2010old male presented with multiple subcutaneous nodules on his right forearm 1\u2003month following an octopus bite at his right wrist. After the disappearance of these lesions, which responded well to low\u2010dose oral prednisone, another type of skin lesion characterized by small, numerous papules reappeared on his right forearm. Histopathologically, a specimen from a subcutaneous nodule showed mostly lobular granulomatous panniculitis, which showed an extensive diffuse infiltrate composed of numerous multinucleated giant cells and epithelioid cells intermingling with lymphocytes and eosinophils. A specimen from a papule that subsequently developed disclosed a diffuse granulomatous dermatitis composed of similar cells and also showed granuloma annulare\u2010like features. This case is considered to be a delayed reaction after an octopus bite showing an unusual giant cell\u2010rich granulomatous dermatitis\/panniculitis. Octopus bites should therefore be included among the marine animal injuries, which cause a delayed\u2010type reaction with granulomatous dermatitis\/panniculitis.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2007.00947.x","type":"journal-article","created":{"date-parts":[[2008,6,10]],"date-time":"2008-06-10T03:56:07Z","timestamp":1213070167000},"page":"1068-1072","source":"Crossref","is-referenced-by-count":7,"title":["Delayed reaction after an octopus bite showing a giant cell\u2010rich granulomatous 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