{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T18:54:38Z","timestamp":1778871278311,"version":"3.51.4"},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,4,12]],"date-time":"2010-04-12T00:00:00Z","timestamp":1271030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>Onychomycosis is a frequently treated fungal infection of the nail plate with morbidity in high\u2010risk populations. The diagnosis often relies on histopathologic analysis of nail plate specimens with the assistance of special stains. Pathologists utilize periodic acid schiff (PAS) and\/or Gomori methenamine silver (GMS) stains to highlight fungi within the nail plate. In a recent study of 51 PAS\u2010negative nail cases, it was concluded that GMS is superior to PAS in the diagnosis of onychomycosis. We expand on this study by investigating a larger number of PAS\u2010negative nail clippings determining whether GMS or PAS is superior in highlighting fungi in additional sections. There was no difference in the sensitivity of PAS vs. GMS (4.2 vs. 4.3%, p = 0.57); however, PAS was found to be significantly less expensive by 2.6\u2010fold. Taken together, these data suggest that the PAS stain is the optimal method for diagnosing onychomycosis.<\/jats:p><jats:p>Barak O, Asarch A, Horn T. PAS is optimal for diagnosing onychomycosis.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2010.01545.x","type":"journal-article","created":{"date-parts":[[2010,4,12]],"date-time":"2010-04-12T08:02:58Z","timestamp":1271059378000},"page":"1038-1040","source":"Crossref","is-referenced-by-count":24,"title":["PAS is optimal for diagnosing onychomycosis"],"prefix":"10.1111","volume":"37","author":[{"given":"Orr","family":"Barak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Asarch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Horn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,16]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(03)00109-8"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.107754"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70397-X"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.03.033"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05029.x"},{"issue":"8","key":"e_1_2_5_7_2","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/ajcp\/25.8_ts.0975","article-title":"A stain for fungi in tissue sections and smears using Gomori's methenamine\u2010silver nitrate technic.","volume":"25","author":"Grocott RG.","year":"1955","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00890.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yadr.2006.07.001"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0560.2010.01545.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0560.2010.01545.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T02:53:03Z","timestamp":1698634383000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0560.2010.01545.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,16]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1111\/j.1600-0560.2010.01545.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0560.2010.01545.x","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,16]]}}}