{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T10:25:31Z","timestamp":1789208731047,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,10,28]],"date-time":"2011-10-28T00:00:00Z","timestamp":1319760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p><jats:italic>Scedosporium apiospermum<\/jats:italic>, the asexual stage of <jats:italic>Pseudoallescheria boydii<\/jats:italic>, is a fungus ubiquitous in soil as well as organically polluted areas, where nitrogen\u2010containing compounds are abundant. It is an emerging opportunistic pathogen that can range from cutaneous to disseminated infection and can be fatal within months of diagnosis. Here we present a case of disseminated <jats:italic>S. apiospermum<\/jats:italic> infection with cutaneous manifestations in a 59\u2010year\u2010old woman with myelodysplastic syndrome, in remission from chronic lymphocytic leukemia, presented with pneumonia and deteriorating mental status. An X\u2010ray computed tomography scan showed three non\u2010contrast\u2010enhancing hypodensities affecting the brain. Many erythematous, indurated skin lesions, measuring 3\u20135 mm in diameter, were noted on her chest, shoulders and arms. Biopsies were submitted for culture and histology. Histopathologic examination revealed superficial and deep perivascular and periadnexal inflammatory infiltrates of lymphocytes and neutrophils. Scattered collections of fungal organisms were noted near the eccrine glands. The periodic acid Schiff with diastase stain showed the presence of variable sized spores and hyphae with some acute angle branching. Both tissue and blood cultures were positive for a single <jats:italic>Scedosporium<\/jats:italic> species. Histologically, eccrine or peri\u2010eccrine involvement by fungi may be an important finding for <jats:italic>Scedosporium<\/jats:italic> infection of the skin.<\/jats:p><jats:p>Harrison MK, Hiatt KH, Smoller BR, Cheung WL. A case of cutaneous <jats:italic>Scedosporium<\/jats:italic> infection in an immunocompromised patient.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2011.01792.x","type":"journal-article","created":{"date-parts":[[2011,10,28]],"date-time":"2011-10-28T06:52:06Z","timestamp":1319784726000},"page":"458-460","source":"Crossref","is-referenced-by-count":7,"title":["A case of cutaneous <i>Scedosporium<\/i> infection in an immunocompromised patient"],"prefix":"10.1111","volume":"39","author":[{"given":"Melody K.","family":"Harrison","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim H.","family":"Hiatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce R.","family":"Smoller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang L.","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,10,28]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200209000-00001"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.01208.x"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200767130-00001"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.52.11.846"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2009.01797.x"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00039-07"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00640.x"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0507.2002.00790.x"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2009.01799.x"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01388-07"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0560.2011.01792.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0560.2011.01792.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T01:29:23Z","timestamp":1698715763000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0560.2011.01792.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,28]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1111\/j.1600-0560.2011.01792.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0560.2011.01792.x","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,28]]}}}