{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:01:22Z","timestamp":1790035282226,"version":"4.0.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,11,12]],"date-time":"2011-11-12T00:00:00Z","timestamp":1321056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>Hybrid schwannoma\/perineurioma represents a recently characterized dermal or subdermal tumor showing schwannian cytomorphology and a perineurioma\u2010like architecture composed of an admixture of both cell types. We report two additional cases of hybrid schwannoma\/ perineurioma, one of which occurred after irradiation. Patient 1 was that of a 33\u2010year\u2010old man presented with a 2.8\u2010cm dermal tumor on his left lower leg. Patient 2 was that of an 89\u2010year\u2010old woman with a history of uterine carcinoma treated by surgery and radiation therapy at the age of 35. She presented with a 1.2 \u00d7 1.0 cm dermal tumor on her left mons pubis with multiple coincidental basal\u2010cell carcinomas around it. Both tumors were microscopically well circumscribed but unencapsulated and situated in the dermis and adipose tissue and showed a vague storiform and lamellar pattern. Cytologically, both tumors contained two\u2010cell populations, i.e. spindled cells with plump nuclei, which were positive for S\u2010100 protein and negative for epithelial membrane antigen (EMA), claudin\u20101 and CD34, as well as cells with very slender nuclei and elongated cytoplasmic processes, which were negative for S\u2010100 protein yet expressed EMA, claudin\u20101 and CD34. Claudin\u20101 was a better marker to highlight cells with very slender nuclei than EMA. Both tumors lacked expression of neurofilament.<\/jats:p><jats:p>Ohata C, Imai N, Hinogami H, Akamatsu K and Sumimura Y. 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