{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:40:46Z","timestamp":1780443646813,"version":"3.54.1"},"reference-count":80,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,3,23]],"date-time":"2012-03-23T00:00:00Z","timestamp":1332460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p>Eosinophils are often present in the inflammatory infiltrate of an interface dermatitis, but the diagnostic specificity of eosinophils in interface dermatitis has not been formally evaluated. We retrospectively identified 97 examples of interface dermatitis with clinically confirmed diagnoses, including lupus erythematosus (LE), lichen planus, pityriasis lichenoides (PL), graft\u2010vs.\u2010host disease (GVHD), dermatomyositis (DM) and drug reaction. Diagnoses were clinically confirmed by at least two dermatologists. Slides were reviewed in a blinded fashion by at least two dermatopathologists. The average eosinophil count per 10 \u00d7200 (\u00d720 objective) fields was lowest for PL (0.2), DM (0.3), GVHD (0.4), and LE (0.5) [defined as Group 1] and was higher for lichen planus, drug reactions, erythema multiforme (major and minor) and viral exanthems [defined as Group 2]. Distinction between Group 1 and Group 2 was maximized using an eosinophil count cutoff of 1.1. In conclusion, eosinophils are usually rare to absent in PL, DM, most forms of LE and GVHD. While final interpretation requires a composite assessment of all features, our results suggest that the presence of even a single eosinophil within nine or ten \u00d720 fields argues against a diagnosis of PL, DM or LE.<\/jats:p>\n                  <jats:p>Sharon VR, Konia TH, Barr KL, Fung MA. Assessment of the \u2018no eosinophils' rule: are eosinophils truly absent in pityriasis lichenoides, connective tissue disease, and graft\u2010vs.\u2010host disease?<\/jats:p>","DOI":"10.1111\/j.1600-0560.2012.01891.x","type":"journal-article","created":{"date-parts":[[2012,2,14]],"date-time":"2012-02-14T09:35:56Z","timestamp":1329212156000},"page":"413-418","source":"Crossref","is-referenced-by-count":47,"title":["Assessment of the \u2018no eosinophils' rule: are eosinophils truly absent in pityriasis lichenoides, connective tissue disease, and graft\u2010vs.\u2010host disease?"],"prefix":"10.1111","volume":"39","author":[{"given":"Victoria R.","family":"Sharon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas H.","family":"Konia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keira L.","family":"Barr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxwell A.","family":"Fung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,23]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"49.","volume-title":"Textbook of dermatopathology","author":"Horn TD.","year":"2004"},{"key":"e_1_2_6_3_2","first-page":"51","volume-title":"Dermatopathology","author":"Ramos\u2010Ceballos FI","year":"2010"},{"key":"e_1_2_6_4_2","unstructured":"ElderDE ed.Lever's histopathology of the skin.Philadelphia:Lippincott Williams & Wilkins 2009."},{"key":"e_1_2_6_5_2","volume-title":"Pathology of the skin.","author":"McKee PH","year":"2005"},{"key":"e_1_2_6_6_2","first-page":"227.","volume-title":"Practical dermatopathology.","author":"Rapini RP.","year":"2005"},{"key":"e_1_2_6_7_2","volume-title":"Skin pathology","author":"Weedon D.","year":"2010"},{"key":"e_1_2_6_8_2","volume-title":"Histologic diagnosis of inflammatory skin diseases.","author":"Ackerman AB.","year":"2005"},{"key":"e_1_2_6_9_2","first-page":"37.","volume-title":"Dermatopathology. 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