{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:00:38Z","timestamp":1782493238746,"version":"3.54.5"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,8,21]],"date-time":"2012-08-21T00:00:00Z","timestamp":1345507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>Follicular mucinosis is currently recognized as a histopathological finding characterized by the accumulation of mucin within follicular epithelium and is commonly associated with follicular mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>). We report the finding of follicular mucinosis in a cutaneous nodule of human T\u2010lymphotropic virus type 1 (<jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101) associated adult T\u2010cell leukemia\/lymphoma (<jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content>). The patient was a 69\u2010year\u2010old female of Caribbean descent with a history of <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content> who presented with erythematous nodules on the chest and abdomen. Histopathologic examination showed a pan\u2010dermal infiltrate of medium\u2010to\u2010large sized atypical lymphocytes extending into follicular epithelium where they associated with large mucin deposits. Immunohistochemical stains showed that the atypical lymphocytes were positive for <jats:styled-content style=\"fixed-case\">CD3<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CD25<\/jats:styled-content> and negative for <jats:styled-content style=\"fixed-case\">CD30<\/jats:styled-content>. Cutaneous lesions of <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content>, which often present histopathologically as an epidermotropic lymphoma with Pautrier\u2010type collections, are often difficult to distinguish from <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>. Until recently, lymphoma\u2010associated follicular mucinosis seemed specific to <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> and S\u00e9zary syndrome (<jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>), being reported only once in a lesion of <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content>. We report a second case of <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content>\u2010associated follicular mucinosis to increase awareness of this possible association, and briefly review the literature of follicular mucinosis\u2010associated hematologic malignancies, ultimately cautioning against the interpretation of all cutaneous lymphoma\u2010related follicular mucinosis as <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2012.01953.x","type":"journal-article","created":{"date-parts":[[2012,8,21]],"date-time":"2012-08-21T10:33:17Z","timestamp":1345545197000},"page":"861-865","source":"Crossref","is-referenced-by-count":12,"title":["Adult T\u2010cell leukemia\/lymphoma with\u00a0follicular mucinosis: an unusual histopathological finding and a commentary"],"prefix":"10.1111","volume":"39","author":[{"given":"Brendan","family":"Camp","sequence":"first","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Horwitz","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa P.","family":"Pulitzer","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,8,21]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198506000-00006"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.124604"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00722.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-11-316794"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.02.007"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb16960.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb08051.x"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/1042819021000055039"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20307"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70161-2"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670030065024"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198404000-00003"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70321-8"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04242.x"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70164-X"},{"key":"e_1_2_4_17_1","first-page":"15","article-title":"Differentiation between cutaneous form of adult T cell leukemia\/lymphoma and cutaneous T cell lymphoma by in situ hybridization using a human T cell leukemia virus\u20101 DNA probe","volume":"144","author":"Arai E","year":"1994","journal-title":"Am J Pathol"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2011.01946.x"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.101"},{"key":"e_1_2_4_20_1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2340\/0001555556163171","article-title":"Histogenesis of mucin in follicular mucinosis. 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