{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:12:58Z","timestamp":1766268778708},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T00:00:00Z","timestamp":1342656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>Bi\u2010clonality is a rare phenomenon seen in approximately 5% of chronic B\u2010cell lymphoproliferative disorders. Both true bi\u2010clonality and somatic hypermutation resulting in intraclonal evolution have been described. We present the case of a 37\u2010year\u2010old female who developed extranodal marginal zone B\u2010cell lymphoma with immunohistochemical studies showing monotypic immunostaining of plasma cells for immunoglobulin lambda light chain on her right arm in 2008. Three years later, she developed a second focus of extranodal marginal zone B\u2010cell lymphoma on her left arm, but immunohistochemical studies demonstrated monotypic immunostaining of plasma cells for immunoglobulin kappa light chain confirmed after repeat analysis. Evaluation for systemic lymphoma with laboratory and imaging studies was negative. Together, the findings were consistent with bi\u2010clonal, multifocal extranodal primary cutaneous marginal zone B\u2010cell lymphoma. We present this case to highlight a rare phenomenon within primary cutaneous marginal zone lymphomas.<\/jats:p>","DOI":"10.1111\/j.1600-0560.2012.01954.x","type":"journal-article","created":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T12:26:24Z","timestamp":1342700784000},"page":"866-871","source":"Crossref","is-referenced-by-count":7,"title":["Bi\u2010clonal, multifocal primary cutaneous marginal zone B\u2010cell lymphoma: report of a case and\u00a0review of the literature"],"prefix":"10.1111","volume":"39","author":[{"given":"Kimberly M.","family":"Nicholson","sequence":"first","affiliation":[{"name":"Department of Pathology, Division of Dermatopathology The University of Texas MD Anderson Cancer Center  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyur P.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Hematopathology The University of Texas MD Anderson Cancer Center  Houston TX 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