{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:07:09Z","timestamp":1762160829210},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T00:00:00Z","timestamp":1240531200000},"content-version":"vor","delay-in-days":10128,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Journal of Haematology"],"published-print":{"date-parts":[[1981,8]]},"abstract":"<jats:p>13 patients with the 5q\u2014 chromosome are described. In 6 patients the 5q\u2014 chromosome was the sole aberration. 10 patients had preleukaemia, 1 a preleukaemia\u2010like syndrome after treatment of polycythaemia vera, a 2 acute myeloid leukaemia. The prognosis was especially poor in terms of survival in preleukaemic patients with 3 or more affected chromosomes: none of these 6 patients survived for more than 6 months. In 4 patients the haematological picture resembled \u2018the 5q\u2014syndrome\u2019. In the long arm of chromosome No 5 deletions of 3 different kinds were detected. They were named according to the size of the 5q\u2014 marker: the short type (10 patients), the intermediate type (1 patient) and the long type (2 patients). There was no clear correlation between the clinical picture and the type of deletion. While the break points cannot always be exactly defined, our data and those reviewed from the literature suggest that the loss of a segment of regions 5q2 or 5q3 is common to all or most deletions.<\/jats:p>","DOI":"10.1111\/j.1600-0609.1981.tb00461.x","type":"journal-article","created":{"date-parts":[[2010,8,3]],"date-time":"2010-08-03T08:25:49Z","timestamp":1280823949000},"page":"119-129","source":"Crossref","is-referenced-by-count":27,"title":["The 5q\u2014 Chromosome in Preleukaemia and Acute Leukaemia"],"prefix":"10.1111","volume":"27","author":[{"given":"L.","family":"Teerenhovi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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