{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T17:59:32Z","timestamp":1759341572616},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T00:00:00Z","timestamp":1240531200000},"content-version":"vor","delay-in-days":10220,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Journal of Haematology"],"published-print":{"date-parts":[[1981,5]]},"abstract":"<jats:p><jats:sup>51<\/jats:sup>Cr\u2010platelet kinetics study was performed in 197 patients with chronic ITP after corticosteroid therapy had failed to induce a long lasting remission. The incidence of splenic, spleno\u2010hepatic, hepatic and diffuse platelet sequestration site was 58 %, 17 %, 6% and 19 %, respectively. Splenic and spleno\u2010hepatic sequestration sites were more frequent in patients less than 30 years old and in patients with a platelet count lower than 50 times 10<jats:sup>9<\/jats:sup>\/1. Ill patients were splenectomized shortly after the study. Normalization of the platelet count was obtained more frequently in patients with splenic and spleno\u2010hepatic sequestration than in the others. Labelled platelet sequestration site was the best predictor of the outcome of splenectomy. Platelet kinetics is a non\u2010invasive investigation that should be performed early after the diagnosis of chronic ITP in all patients eligible for splenectomy.<\/jats:p>","DOI":"10.1111\/j.1600-0609.1981.tb01682.x","type":"journal-article","created":{"date-parts":[[2010,8,4]],"date-time":"2010-08-04T21:57:14Z","timestamp":1280959034000},"page":"407-412","source":"Crossref","is-referenced-by-count":25,"title":["Chronic Idiopathic Thrombocytopenic Purpura (ITP): Site of Platelet Sequestration and Results of 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