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Discriminant analysis was applied to both haematological and erythrokinetic parameters of the two disease groups. Plasma iron concentration and MCV were significantly higher in AA, and allowed a perfect separation of the patients. As regards erythrokinetics, values of ineffective erythropoiesis and peripheral haemolysis were able to separate completely the two disease groups, being significantly lower in HCL than in AA. A true erythroid failure was the peculiar erythrokinetic pattern of HCL. This conclusion allows one to speculate on the nature of the stem cell damage in this disease.<\/jats:p>","DOI":"10.1111\/j.1600-0609.1982.tb00501.x","type":"journal-article","created":{"date-parts":[[2010,8,4]],"date-time":"2010-08-04T23:20:25Z","timestamp":1280964025000},"page":"97-102","source":"Crossref","is-referenced-by-count":3,"title":["Erythropoiesis in Hairy Cell Leukaemia: A True Erythroid Failure"],"prefix":"10.1111","volume":"28","author":[{"given":"Ester","family":"Orlandi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Alessandrino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Baraldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Barosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Berzuini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Cazzola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Spriano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,4,24]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1978.tb01112.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4809(78)90008-3"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-2-228"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1979.tb01123.x"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-708X(76)90047-8"},{"key":"e_1_2_1_7_1","first-page":"282","article-title":"Impaired hemopoietic function of bone marrow in leukemic reticuloendo\u2010theliosis","volume":"17","author":"Chaudry A A","year":"1976","journal-title":"Proc Am Soc Clin Oncologists"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.27.3.231"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1080\/00401706.1977.10489590","article-title":"Selection of variables in discriminant analysis by F statistic and error rate","volume":"191","author":"Habbena J D S","year":"1977","journal-title":"Technometrics"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1980.tb07189.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)91066-0"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1977.tb00594.x"},{"key":"e_1_2_1_13_1","first-page":"82","volume-title":"Aplastic Anaemia","author":"Lewis S M","year":"1979"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000207307"},{"key":"e_1_2_1_15_1","first-page":"224","article-title":"Prediction of blood volume in normal human adults","volume":"51","author":"Nadler S B","year":"1972","journal-title":"Surgery"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)90226-2"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197811000-00001"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1963.10500845"},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1001\/archinte.1972.03650020074014","article-title":"Leukemic reticuloendothelisosis. 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