{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T14:42:29Z","timestamp":1773240149219,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> The <jats:italic>WT1<\/jats:italic> gene is considered to be highly expressed in patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia and chronic myeloid leukemia and is thought to play a key role in maintaining the viability of leukemia cells. However, little is known about the <jats:italic>WT1<\/jats:italic> gene expression levels in pediatric patients with juvenile myelo\u2010monocytic leukemia (JMML) and myelodysplastic syndromes (MDS). We studied <jats:italic>WT1<\/jats:italic> expression in diagnostic bone marrow (BM) and peripheral blood (PB) samples of 90 patients with JMML, low grade MDS, advanced MDS and myelodysplasia\u2010related AML in BM (<jats:italic>n<\/jats:italic>\u2003=\u200320) and PB (<jats:italic>n<\/jats:italic>\u2003=\u200318) samples of normal healthy volunteer donors.<\/jats:p>","DOI":"10.1111\/j.1600-0609.2004.00260.x","type":"journal-article","created":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T15:46:49Z","timestamp":1086104809000},"page":"25-28","source":"Crossref","is-referenced-by-count":26,"title":["<i>WT1<\/i> gene expression: useful marker for minimal residual disease in childhood myelodysplastic syndromes and juvenile myelo\u2010monocytic leukemia?"],"prefix":"10.1111","volume":"73","author":[{"given":"Peter","family":"Bader","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Niemeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerrit","family":"Weber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiziana","family":"Coliva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Kreyenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Gerecke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Biondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,6]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000027063"},{"key":"e_1_2_5_3_2","first-page":"3534","article-title":"Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG\u2010MDS)","volume":"89","author":"Niemeyer CM","year":"1997","journal-title":"Blood"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402765"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V90.2.479"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2000.01927.x"},{"key":"e_1_2_5_7_2","first-page":"1060","article-title":"Presence of Wilms\u2019 tumor gene (WT1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias","volume":"9","author":"Menssen HD","year":"1995","journal-title":"Leukemia"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.annonc.a059321"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402512"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.11.4396b.4396b"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.4.1405"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.6.2267.bloodjournal8862267"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V90.3.1217"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401341"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.10.503"},{"key":"e_1_2_5_16_2","first-page":"965","article-title":"Abnormal expression of the Wilms'tumor gene WT1 in juvenile chronic myeloid leukemia and infantile monosomy 7 syndrome","volume":"22","author":"Sako M","year":"1998","journal-title":"Leukemia Res"}],"container-title":["European Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0609.2004.00260.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0609.2004.00260.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0609.2004.00260.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T15:04:11Z","timestamp":1697209451000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0609.2004.00260.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["10.1111\/j.1600-0609.2004.00260.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0609.2004.00260.x","archive":["Portico"],"relation":{},"ISSN":["0902-4441","1600-0609"],"issn-type":[{"value":"0902-4441","type":"print"},{"value":"1600-0609","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}