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Among diagnostic procedures frequent use is reported for arterial O<jats:sub>2<\/jats:sub> saturation, spleen size determination, bone marrow histology, serum erythropoietin, serum cobalamins and leukocyte alkaline phosphatase score, while direct determination of the red blood cell mass is used infrequently (seldom or never by 82%). Among therapeutic modalities hydroxyurea and phlebotomy alone were most frequently used. The <jats:sup>32<\/jats:sup>P therapy was used at least sometimes by 57% of the physicians, and more widely in the university clinics. Anagrelide and alfa\u2010interferon was used in a minority of patients only. The use of prophylactic acetylsalicylic acid was very variable. The majority of the physicians had an aim for their phlebotomy treatment at a level of 0.45 or less, but 21% used a level of 0.46\u20130.49 and 8% a level of 0.55\u20130.60 (in younger patients). The platelet level, at which myelosuppressive therapy was initiated, also varied, from 400\u2003\u00d7\u200310<jats:sup>9<\/jats:sup>\/L to &gt;1500\u2003\u00d7\u200310<jats:sup>9<\/jats:sup>\/L. It can be concluded that in practical clinical work in Sweden the diagnosis of PV is established by frequent use of serum erythropoietin, bone marrow examination and spleen size determination. The use of different therapeutic modalities is very variable. Many physicians carry out their phlebotomy treatment with less intensity compared with national and international recommendations.<\/jats:p>","DOI":"10.1111\/j.1600-0609.2005.00424.x","type":"journal-article","created":{"date-parts":[[2005,5,5]],"date-time":"2005-05-05T19:56:31Z","timestamp":1115322991000},"page":"489-495","source":"Crossref","is-referenced-by-count":16,"title":["Management of patients with polycythaemia vera: results of a survey among Swedish haematologists"],"prefix":"10.1111","volume":"74","author":[{"given":"Bj\u00f6rn","family":"Andreasson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"L\u00f6fvenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Westin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,5]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-9-199511010-00003"},{"key":"e_1_2_6_3_2","first-page":"339","article-title":"Diagnosis and classification of the polycythemias","volume":"12","author":"Berlin NI.","year":"1975","journal-title":"Semin Hematol"},{"issue":"1","key":"e_1_2_6_4_2","first-page":"87","article-title":"The diagnostic criteria of polycythaemia rubra vera","volume":"22","author":"Pearson TC","year":"1996","journal-title":"Leuk Lymphoma"},{"key":"e_1_2_6_5_2","first-page":"20","volume-title":"World Health Organization Classification of Tumours","author":"WHO","year":"2001"},{"key":"e_1_2_6_6_2","article-title":"Polycytemia vera, essentiell trombocytemi och myelofibros. 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