{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:49:30Z","timestamp":1772160570376,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T00:00:00Z","timestamp":1179705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective:\u2002<\/jats:bold>\n                    Both carcinoma of the prostate and non\u2010Hodgkin\u2019s lymphoma are common in elderly patients. Measurement of serum prostate\u2010specific antigen (PSA) is a frequently used tool to diagnose and monitor prostate carcinoma and is generally specific for diseases of the prostate.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Case:\u2002<\/jats:bold>\n                    We describe a 68\u2010yr\u2010old patient with voiding difficulties and high PSA levels, but without inflammatory or malignant changes upon multiple transrectal ultrasound guided prostate biopsies. Digital rectal examination was normal. Laboratory showed a strongly elevated PSA level (62\u2003\u03bcg\/L, Immulight 2000\n                    <jats:sup>\u00ae<\/jats:sup>\n                    ; DPC, USA). A CT\u2010scan showed a retroperitoneal process with mass in the right pelvis and infiltration of the bladder wall, suggestive for metastatic prostate carcinoma. Surgical excision of an axillary lymph node set the diagnosis at a stage IV follicular lymphoma, Berard grade I to II in which the majority of neoplastic cells expressed PSA. After lymphoma\u2010specific treatment, there was a positron emission tomography (PET) confirmed complete remission with normal PSA levels (6\u2003\u03bcg\/L), which still persists.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:\u2002<\/jats:bold>\n                    Although rare, high PSA levels can be due to the presence of non\u2010Hodgkin\u2019s lymphoma. Such a diagnosis should be considered when patients present with lymphadenopathy other than regional prostatic lymphadenopathy.\n                  <\/jats:p>","DOI":"10.1111\/j.1600-0609.2007.00883.x","type":"journal-article","created":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T10:37:11Z","timestamp":1183199831000},"page":"155-158","source":"Crossref","is-referenced-by-count":8,"title":["High levels of serum prostate\u2010specific antigen due to PSA producing follicular non\u2010Hodgkin\u2019s lymphoma"],"prefix":"10.1111","volume":"79","author":[{"given":"Jan Jelrik","family":"Oosterheert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo M.","family":"Budel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter","family":"Vos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shulamiet","family":"Wittebol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,6,19]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.54.1.8"},{"key":"e_1_2_4_3_2","unstructured":"Dutch National Public Health Compass Available at:http:\/\/www.nationaalkompas.nl. 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