{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:50:22Z","timestamp":1789159822188,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,6,25]],"date-time":"2012-06-25T00:00:00Z","timestamp":1340582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Non\u2010myeloablative conditioning hematopoietic cell transplantation (<jats:styled-content style=\"fixed-case\">NMC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content>) has improved the treatment of chronic lymphocytic leukemia (<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>) and follicular lymphoma (<jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>). In a cohort of 85 patients (45 with <jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content> and 40 with <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>), we observed 5\u2010yr overall survival (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>) and progression\u2010free survival (<jats:styled-content style=\"fixed-case\">PFS<\/jats:styled-content>) of 53% and 38% in the <jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content> group and 81% and 76% in the <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> group. In the both the <jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content> group and the <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> group, a strong trend toward better <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PFS<\/jats:styled-content> was observed among patients in complete remission (<jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>) at <jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content>. Within the <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> group, sixteen patients had at one or more time points in their disease history had transformed <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>. In contrast to the poor survival found in patients with transformed <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> in previous studies, the 5\u2010yr <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> was almost identical in patients with transformed and non\u2010transformed <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>, 83% and 78%, respectively. In conclusion, our study supports that <jats:styled-content style=\"fixed-case\">NMC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content> is a safe and efficacious treatment that can provide long\u2010term survival in elderly, heavily pretreated patients with <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>. Especially patients with <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>, and also transformed <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>, seemed to have a great benefit of <jats:styled-content style=\"fixed-case\">NMC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content> at the time of <jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content> was an important prognostic factor.<\/jats:p>","DOI":"10.1111\/j.1600-0609.2012.01801.x","type":"journal-article","created":{"date-parts":[[2012,5,10]],"date-time":"2012-05-10T13:39:55Z","timestamp":1336657195000},"page":"151-159","source":"Crossref","is-referenced-by-count":7,"title":["Single\u2010institution long\u2010term outcomes for patients receiving nonmyeloablative conditioning hematopoeitic cell transplantation for chronic lymphocytic leukemia and follicular lymphoma"],"prefix":"10.1111","volume":"89","author":[{"given":"Bo K.","family":"Mortensen","sequence":"first","affiliation":[{"name":"Allogeneic Hematopoietic Cell Transplantation Laboratory, Department of Hematology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren L.","family":"Petersen","sequence":"additional","affiliation":[{"name":"Allogeneic Hematopoietic Cell Transplantation Laboratory, Department of Hematology Rigshospitalet  Copenhagen Denmark"},{"name":"Department of Hematology, Hematopoetic Cell Transplantation Unit Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Kornblit","sequence":"additional","affiliation":[{"name":"Allogeneic Hematopoietic Cell Transplantation Laboratory, Department of Hematology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per 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