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The objective of this study was to use exploratory data analysis methods to identify potential clinical psoriasis phenotypes without <jats:italic>a priori<\/jats:italic> hypotheses. A prospective questionnaire\u2010based survey collected comprehensive informations on the main clinical characteristics of 1484 psoriatic patients. Six statistically different clusters of clinical symptoms were observed, corresponding at least to six different clinical psoriasis phenotypes. Moreover, discriminant functions allow patients to be assigned to one or other of these phenotypes. Our findings open the way to focus genetic, pharmaco\u2010genetic, pathophysiological and therapeutic studies on more homogenous group of patients.<\/jats:p>","DOI":"10.1111\/j.1600-0625.2009.00871.x","type":"journal-article","created":{"date-parts":[[2009,3,30]],"date-time":"2009-03-30T17:45:53Z","timestamp":1238435153000},"page":"712-719","source":"Crossref","is-referenced-by-count":30,"title":["Psoriasis: characterization of six different clinical phenotypes"],"prefix":"10.1111","volume":"18","author":[{"given":"Christiane","family":"Guinot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Latreille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Perrussel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nejib","family":"Doss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Dubertret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the French Psoriasis Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,7,24]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"Psoriasis. 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