{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:03:59Z","timestamp":1792674239734,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,3,28]],"date-time":"2011-03-28T00:00:00Z","timestamp":1301270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> In cutaneous wound healing, the role of oxygen <jats:italic>in vivo<\/jats:italic> is poorly understood. We studied wound surface pO<jats:sub>2<\/jats:sub> during physiological wound healing in humans. Split\u2010thickness skin graft donor sites (<jats:italic>n<\/jats:italic>\u2003=\u200312) served as standardized wound models. Wound surface pO<jats:sub>2<\/jats:sub> was measured at 1, 6 and 14\u2003days after split\u2010skin harvesting using two\u2010dimensional luminescence lifetime imaging (2D\u2010LLI) of palladium(II)\u2010meso\u2010tetraphenyl\u2010tetrabenzoporphyrin (Pd\u2010TPTBP) in polystyrene\u2010co\u2010acrylonitrile (PSAN) particles on transparent foils. In another experiment, we removed the stratum corneum (SC) on the volar forearm (<jats:italic>n<\/jats:italic>\u2003=\u200310) by tape strippings to study the impact of the SC on the epidermal oxygen barrier. Split\u2010skin donor site pO<jats:sub>2<\/jats:sub> significantly decreased during the time course of physiological healing. Regional differences in pO<jats:sub>2<\/jats:sub> within donor site wounds were visualized for the first time in literature. No difference was found in pO<jats:sub>2<\/jats:sub> before and after SC removal, showing that the SC is not a major constituent of the epidermal oxygen barrier.<\/jats:p>","DOI":"10.1111\/j.1600-0625.2011.01263.x","type":"journal-article","created":{"date-parts":[[2011,3,28]],"date-time":"2011-03-28T18:01:15Z","timestamp":1301335275000},"page":"550-554","source":"Crossref","is-referenced-by-count":59,"title":["2D luminescence imaging of physiological wound oxygenation"],"prefix":"10.1111","volume":"20","author":[{"given":"Stephan","family":"Schreml","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Meier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto S.","family":"Wolfbeis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Maisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf\u2010Markus","family":"Szeimies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Landthaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Regensburger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Santarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Klimant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Babilas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,28]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909023411006"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.10.048"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03413.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09804.x"},{"key":"e_1_2_7_6_2","author":"Schreml S","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2010.01190.x"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2007.00264.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0711642105"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1953.6.3.189"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/10739680591003314"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2008.00295.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3233\/CH-2008-1134","volume":"40","author":"Geis S","year":"2008","journal-title":"Clin Hemorheol Microcirc"},{"key":"e_1_2_7_14_2","first-page":"39","volume":"15","author":"Clark L C","year":"1979","journal-title":"Birth Defects Orig Artic Ser"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200702276"},{"key":"e_1_2_7_16_2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2340\/0001555574375379","volume":"74","author":"Ohman H","year":"1994","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1159\/000211078"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0846.2003.00036.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-003-0662-7"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2001.013067"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00911.x"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1039\/b501536g"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac801521v"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2009.05.018"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.200500778"},{"key":"e_1_2_7_26_2","first-page":"183","volume":"20","author":"Stern G","year":"1919","journal-title":"Zeitschrift f\u00fcr Physik"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(83)90136-1"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/193293a0"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e31818790b4"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3181d37624"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.10.1252"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0183"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310015419"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2004.00067.x"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1987.tb02585.x"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.05.048"},{"key":"e_1_2_7_37_2","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1097\/00006534-199705010-00023","volume":"99","author":"Niezgoda J A","year":"1997","journal-title":"Plast Reconstr Surg"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0625.2011.01263.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0625.2011.01263.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T15:49:12Z","timestamp":1697384952000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0625.2011.01263.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,28]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1111\/j.1600-0625.2011.01263.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0625.2011.01263.x","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,28]]}}}