{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T12:17:42Z","timestamp":1790511462664,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,5,24]],"date-time":"2012-05-24T00:00:00Z","timestamp":1337817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>\n                    <jats:bold>Abstract:\u00a0<\/jats:bold>\n                    Malignant Sezary cells express the natural killer (NK) receptors KIR3DL2 (CD158k) and Nkp46 and may co\u2010express activating killer immunoglobulin\u2010like receptors (KIR) that may participate to neoplastic T\u2010cell activation through the JNK pathway. Little is known regarding NK receptor expression in other cutaneous T\u2010cell lymphomas. We studied the expression of KIR and natural cytotoxicity receptor (NCR) transcripts, and KIR3DL1\/2 at the protein level, in 16 skin biopsies from 10 patients with transformed mycosis fungoides (tMF). Some KIR and NCR transcripts were found in all cases, with various repertoires. Two to nine different KIR receptors were expressed in a single biopsy. Among them, KIR3DL2 was the most frequent, with the highest level of expression in quantitative analyses and correlated with\n                    <jats:italic>in situ<\/jats:italic>\n                    protein expression, while phosphorylated JNK was never detected. Among NCR, NKp46 was expressed in all investigated cases. The role of KIR3DL2 and NKp46 in tMF oncogenesis remains to be studied.\n                  <\/jats:p>","DOI":"10.1111\/j.1600-0625.2012.01489.x","type":"journal-article","created":{"date-parts":[[2012,3,24]],"date-time":"2012-03-24T08:39:06Z","timestamp":1332578346000},"page":"461-463","source":"Crossref","is-referenced-by-count":43,"title":["CD158k\/KIR3DL2 and NKp46 are frequently expressed in transformed mycosis fungoides"],"prefix":"10.1111","volume":"21","author":[{"given":"Nicolas","family":"Ortonne","sequence":"first","affiliation":[{"name":"Department of Pathology, AP\u2010HP, Groupe Hospitalier Henri Mondor \u2013 Albert Chenevier, Henri Mondor Hospital Cr\u00e9teil France"},{"name":"INSERM Unit 955 \u00c9quipe 9, Henri Mondor Hospital  Cr\u00e9teil France"},{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 Paris Est, UMR\u2010S 955  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Le Gouvello","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 Paris Est, UMR\u2010S 955  Cr\u00e9teil France"},{"name":"Department of Biological Immunology, AP\u2010HP, Groupe Hospitalier Henri Mondor \u2013 Albert Chenevier, Henri Mondor Hospital  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reka","family":"Tabak","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Semmelweis Egyetem Borgyogyaszati Klinika  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Marie\u2010Cardine","sequence":"additional","affiliation":[{"name":"INSERM U976, Saint\u2010Louis Hospital  Paris Cedex France"},{"name":"Laboratory of Immunology, Dermatology &amp; Oncology, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, UMR\u2010S 976  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Setiao","sequence":"additional","affiliation":[{"name":"Department of Pathology, AP\u2010HP, Groupe Hospitalier Henri Mondor \u2013 Albert Chenevier, Henri Mondor Hospital Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Berrehar","sequence":"additional","affiliation":[{"name":"Department of Biological Immunology, AP\u2010HP, Groupe Hospitalier Henri Mondor \u2013 Albert Chenevier, Henri Mondor Hospital  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Nghe\u2010Tang","sequence":"additional","affiliation":[{"name":"Department of Pathology, AP\u2010HP, Groupe Hospitalier Henri Mondor \u2013 Albert Chenevier, Henri Mondor Hospital Cr\u00e9teil France"},{"name":"INSERM Unit 955 \u00c9quipe 9, Henri Mondor Hospital  Cr\u00e9teil France"},{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 Paris Est, UMR\u2010S 955  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Pathology, AP\u2010HP, Groupe Hospitalier Henri Mondor \u2013 Albert Chenevier, Henri Mondor Hospital Cr\u00e9teil France"},{"name":"INSERM Unit 955 \u00c9quipe 9, Henri Mondor Hospital  Cr\u00e9teil France"},{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 Paris Est, UMR\u2010S 955  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Bagot","sequence":"additional","affiliation":[{"name":"INSERM U976, Saint\u2010Louis Hospital  Paris Cedex France"},{"name":"Laboratory of Immunology, Dermatology &amp; Oncology, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, UMR\u2010S 976  Paris France"},{"name":"Department of Dermatology, Hospital Saint\u2010Louis  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armand","family":"Bensussan","sequence":"additional","affiliation":[{"name":"INSERM U976, Saint\u2010Louis Hospital  Paris Cedex France"},{"name":"Laboratory of Immunology, Dermatology &amp; Oncology, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, UMR\u2010S 976  Paris France"},{"name":"Department of Dermatology, Hospital Saint\u2010Louis  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,24]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-10-4239"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.404"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09364.x"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701013"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.20395"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.5.2767"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.6.3725"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.11.6719"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.2.1138"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1251"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80394-5"},{"key":"e_1_2_10_13_2","first-page":"415","volume-title":"Leukocyte Typing VII","author":"Parolini S","year":"2002"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-02-071993"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64114-4"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2004.00176.x"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.8"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20060028"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65372-2"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2006.00419.x"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2009.00993.x"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0625.2012.01489.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0625.2012.01489.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T04:55:05Z","timestamp":1698641705000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0625.2012.01489.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,24]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1600-0625.2012.01489.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0625.2012.01489.x","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,24]]}}}