{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T08:59:33Z","timestamp":1778921973216,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2007,12,18]],"date-time":"2007-12-18T00:00:00Z","timestamp":1197936000000},"content-version":"vor","delay-in-days":47,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:p> <jats:italic>Helicobacter pylori <\/jats:italic>can infect the human stomach through the ingestion of water. Only a few studies on the morphological changes and viability of this bacteria in DGW (deep ground water) have been reported and none in natural seawater (SW). Morphological changes and the culturability of <jats:italic>H. pylori <\/jats:italic>after storage in DGW or SW for a week were examined to see if they could be a factor associated with the high infection rate in Japan. An<jats:italic> H. pylori<\/jats:italic> strain, ATCC 43504, stored in DGW and in SW at 4\u2003\u00b0C for 7 days, was examined daily for any ultrastructural changes and culturability. The same <jats:italic>H. pylori<\/jats:italic> strain was also cultured in conventional <jats:italic>Brucella <\/jats:italic>broth culture liquid medium as control and was similarly observed. Bacteria kept in DGW and SW were found not only to retain their spiral form but also to show better culturability than those kept in the control nutrient\u2010rich medium (p&lt;0.01). Thus, natural waters were found to be more conducive to <jats:italic>H. pylori <\/jats:italic>survival than a nutrient\u2010rich medium.<\/jats:p>","DOI":"10.1111\/j.1600-0643.2007.00594.x","type":"journal-article","created":{"date-parts":[[2009,1,22]],"date-time":"2009-01-22T12:34:52Z","timestamp":1232627692000},"page":"1285-1291","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["<i>Helicobacter pylori<\/i>: longer survival in deep ground water and sea water than in a nutrient\u2010rich environment"],"prefix":"10.1111","volume":"115","author":[{"given":"KOHEI","family":"KONISHI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NAGAHITO","family":"SAITO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ERIKO","family":"SHOJI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HIROSHI","family":"TAKEDA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MOTOTSUGU","family":"KATO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MASAHIRO","family":"ASAKA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HONG\u2010KEAN","family":"OOI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,12,18]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)91816-6"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)90156-S"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/516067"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.2004.01529.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2001.tb02652.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2005.00335.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8612990"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-48-10-971"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.43.7.609-b"},{"key":"e_1_2_6_11_2","first-page":"187","article-title":"Helicobacter pylori in culture: an ultrastructural study","volume":"75","author":"Sato F","year":"2000","journal-title":"Hokkaido J Med Sci"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/jinf.2002.1047"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00795-003-0214-3"},{"key":"e_1_2_6_14_2","first-page":"17","article-title":"Diagnostic possibilities for Campylobacter pylori infection","volume":"1","author":"Alpert LC","year":"1989","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.05146-0"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1128\/aem.59.4.1231-1235.1993","article-title":"Use of autoradiography to assess viability of Helicobacter pylori in water","volume":"59","author":"Shahamat M","year":"1993","journal-title":"Appl Environ Microbiol"},{"key":"e_1_2_6_17_2","first-page":"324","article-title":"The fate of enteric pathogenic bacteria in estuarine and marine environments","volume":"3","author":"Grimes DJ","year":"1986","journal-title":"Microbiol Sci"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8840(11)80964-3"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01545314"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529109093209"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1998.tb01386.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2004.tb09724.x"},{"key":"e_1_2_6_23_2","doi-asserted-by":"crossref","first-page":"5263","DOI":"10.1128\/JB.180.19.5263-5268.1998","article-title":"Nucleotide sequence and characterization of cdrA, a cell division\u2010related gene of Helicobacter pylori","volume":"180","author":"Takeuchi H","year":"1998","journal-title":"J Bacteriol"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01591357"},{"key":"e_1_2_6_25_2","first-page":"103","article-title":"Is the coccoid form of Helicobacter pylori viable?","volume":"87","author":"Hua J","year":"1996","journal-title":"Microbios"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.65.9.3672-3679.1997"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.2.459"},{"key":"e_1_2_6_28_2","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1128\/iai.64.6.2331-2335.1996","article-title":"Changes in Helicobacter pylori ultrastructure and antigens during conversion from the bacillary to the coccoid form","volume":"64","author":"Benassa M","year":"1996","journal-title":"Infect Immun"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-139-12-3029"}],"container-title":["APMIS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0643.2007.00594.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0643.2007.00594.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T17:59:41Z","timestamp":1697047181000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0643.2007.00594.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["10.1111\/j.1600-0643.2007.00594.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0643.2007.00594.x","archive":["Portico"],"relation":{},"ISSN":["0903-4641","1600-0463"],"issn-type":[{"value":"0903-4641","type":"print"},{"value":"1600-0463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11]]},"assertion":[{"value":"2007-12-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}