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Underreporting due to patients not seeking medical care as well as failure to identify anaphylaxis affects our understanding of the magnitude of the disease. Treatment with intramuscular epinephrine continues to be the recommended first\u2010line therapy, although studies indicate that education of both the patients and the medical community is needed. Adverse food reactions continue to be the leading cause of anaphylaxis presenting for emergency care. Current therapy for food\u2010induced anaphylaxis is built on the foundation of strict dietary avoidance, rapid access to injectable epinephrine, and education to recognize signs and symptoms of anaphylaxis. Investigation into therapy with oral and sublingual immunotherapy as well as other modalities holds hope for improved treatment of food\u2010induced anaphylaxis.<\/jats:p>","DOI":"10.1111\/j.1600-065x.2011.01028.x","type":"journal-article","created":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T10:29:11Z","timestamp":1308565751000},"page":"247-257","source":"Crossref","is-referenced-by-count":52,"title":["Anaphylaxis: a history with emphasis on food allergy"],"prefix":"10.1111","volume":"242","author":[{"given":"Stephen R.","family":"Boden","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Wesley Burks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,6,20]]},"reference":[{"key":"e_1_2_17_2_2","volume-title":"Lectures on Blood","author":"Megendie 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