{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T13:56:18Z","timestamp":1722779778404},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,5,4]],"date-time":"2006-05-04T00:00:00Z","timestamp":1146700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Strongyloides infection may result in clinical disease or confound experimental protocols that utilize non\u2010human primates. There is presently a <jats:italic>Strongyloides fulleborni<\/jats:italic> infection rate of approximately 27% in the Tulane National Primate Research Center's breeding colonies despite the routine therapeutic and prophylactic use of ivermectin.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> A study was conducted to determine if moxidectin treatment offers advantages to the intestinal parasite control program. A total of 150 rhesus macaques (<jats:italic>Macaca mulatta<\/jats:italic>) that were removed from the breeding colonies due to illness were selected for the study. The animals were randomly assigned to treatment groups with 75 receiving ivermectin and 75 receiving moxidectin. Egg counts were performed on fecal samples collected pre\u2010 and post\u2010treatment.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Both treatments resulted in decreases in the number of eggs\/g in the post\u2010treatment sample as compared with the pre\u2010treatment sample; however, no significant difference was found between treatment groups.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> With the data demonstrating a similar efficacy in both ivermectin and moxidectin treated macaques, the benefit of moxidectin treatment relates to biosafety and topical application.<\/jats:p>","DOI":"10.1111\/j.1600-0684.2006.00154.x","type":"journal-article","created":{"date-parts":[[2006,5,4]],"date-time":"2006-05-04T15:19:48Z","timestamp":1146755988000},"page":"172-176","source":"Crossref","is-referenced-by-count":15,"title":["Comparison of efficacy of moxidectin and ivermectin in the treatment of <i>Strongyloides fulleborni<\/i> infection in rhesus macaques"],"prefix":"10.1111","volume":"35","author":[{"given":"Jason P.","family":"Dufour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank B.","family":"Cogswell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrine M.","family":"Phillippi\u2010Falkenstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf P.","family":"Bohm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,5,4]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"Survey of Enzootic Pathogens and Arthropod Vectors","author":"Cogswell FB","year":"2004"},{"key":"e_1_2_6_3_2","volume-title":"Personal Communication and Package Insert, Cydectin Moxideation Pour\u2010on for Beef and Dairy Cattle Antiparasite","author":"Fort Dodge Animal Health","year":"2002"},{"key":"e_1_2_6_4_2","first-page":"102","volume-title":"The Laboratory Nonhuman Primate","author":"Fortman JD","year":"2002"},{"key":"e_1_2_6_5_2","first-page":"765","volume-title":"Laboratory Animal Medicine","author":"Fox JG","year":"2002"},{"key":"e_1_2_6_6_2","first-page":"748","volume-title":"Current Veterinary Therapy Food Animal Practice","author":"Howard JL","year":"1993"},{"key":"e_1_2_6_7_2","first-page":"65","article-title":"Usefulness of Kato\u2013Katz and trichome staining as diagnostic methods for parasitic infections in clinical laboratories","volume":"3","author":"Idris MA","year":"2001","journal-title":"SQU Journal for Scientific Research, Medical Sciences"},{"key":"e_1_2_6_8_2","volume-title":"Moxidectin","author":"International Program on Chemical Safety","year":"2003"},{"key":"e_1_2_6_9_2","volume-title":"Parasites and Parasitic Diseases of Domestic Animals","author":"Johnstone C","year":"1998"},{"key":"e_1_2_6_10_2","first-page":"2146","volume-title":"Physician's Desk Reference","author":"Physician's Desk Reference","year":"2005"},{"key":"e_1_2_6_11_2","first-page":"378","volume-title":"Veterinary Drug Handbook","author":"Plumb DC","year":"1995"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1996.11813075"}],"container-title":["Journal of Medical Primatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0684.2006.00154.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0684.2006.00154.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T05:11:43Z","timestamp":1698729103000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0684.2006.00154.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5,4]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1111\/j.1600-0684.2006.00154.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0684.2006.00154.x","archive":["Portico"],"relation":{},"ISSN":["0047-2565","1600-0684"],"issn-type":[{"value":"0047-2565","type":"print"},{"value":"1600-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,5,4]]}}}