{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:41:03Z","timestamp":1792176063046,"version":"4.4.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T00:00:00Z","timestamp":1217203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Thirty\u2010four wild <jats:italic>Chlorocebus \u00a0aethiops<\/jats:italic> monkeys were trapped for research purposes.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> During routine quarantine check\u2010up, cerebrospinal fluid (CSF) and blood were microscopically examined for parasites. Estimations of CSF protein levels were made by the biuret method and the white cell counts by the hemocytometer.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Seven monkeys demonstrated microfilariae in blood and CSF. This was accompanied by a two\u2010 and ninefold increase in CSF total protein and white cell counts, respectively. Necropsy of one of the blood and CSF microfilariae\u2010positive animals revealed the presence of adult worms in the brain meninges. The parasites were identified as the zoonotic filaroid nematode <jats:italic>Meningonema peruzii<\/jats:italic>.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Wild <jats:italic>C.\u00a0aethiops<\/jats:italic> monkeys developed CSF changes resulting, most probably, from infection with <jats:italic>M.\u00a0peruzii.<\/jats:italic> Moreover, the monkeys could be acting as an important reservoir. The study highlights the need for epidemiological and pathogenological studies of this parasite, which is of public health significance. Moreover, <jats:italic>C.\u00a0aethiops<\/jats:italic> proved to be a useful primate model for the study of this zoonotic infection.<\/jats:p>","DOI":"10.1111\/j.1600-0684.2008.00282.x","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T09:07:20Z","timestamp":1217236040000},"page":"210-214","source":"Crossref","is-referenced-by-count":4,"title":["Biochemical changes in cerebrospinal fluid of <i>Chlorocebus \u00a0aethiops<\/i> naturally infected with zoonotic <i>Meningonema \u00a0peruzzii<\/i>"],"prefix":"10.1111","volume":"37","author":[{"given":"R.M.","family":"Ngure","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Karanja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.K.","family":"Mungatana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.N.","family":"Wamae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Ngotho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.W.","family":"Gichuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7,28]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"173","article-title":"A new zoonosis of the cerebrospinal fluid of man probably caused by Meningonema \u00a0peruzzii, a filaria of the central nervous system of Cercopithecidae","volume":"2","author":"Boussinesq M","year":"1995","journal-title":"Parasitol"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1988.tb00317.x"},{"key":"e_1_2_7_4_2","first-page":"21","article-title":"Cerebral filariasis caused by Acanthocheilonema\u00a0perstans","volume":"14","author":"Dukes DC","year":"1968","journal-title":"C Afric J Med"},{"key":"e_1_2_7_5_2","first-page":"169","volume-title":"Handbook of Laboratory Animal Science","author":"Farah IO","year":"2005"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-012775390-4\/50235-9"},{"key":"e_1_2_7_7_2","unstructured":"GichukiCW KaranjaSM NgureRM KamauDM OtsyulaMG:Co\u2010infection of vervet monkeys with trypanosomes and SIV leads to rapid disease progression and renders trypanocidal therapy ineffective. 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