{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:41:10Z","timestamp":1762375270284},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,5,5]],"date-time":"2008-05-05T00:00:00Z","timestamp":1209945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> A focal hypointense intracranial lesion was detected by magnetic resonance imaging in the right caudal occipital lobe of the cerebrum in an asymptomatic cynomolgus macaque (<jats:italic>Macaca fascicularis<\/jats:italic>).<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Following euthanasia, gross evaluation of the lesion revealed a 1\u2003cm diameter, wedge\u2010shaped intracranial cavitation without apparent communication with the ventricles. Histologically, the lesion was lined by ciliated cuboidal to low columnar epithelium that showed immunopositivity for cytokeratin, S\u2010100, and GFAP.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Based upon the gross, histologic, and immunohistochemical findings, this lesion was classified as an ependymal cyst. In the human patients, ependymal cysts are benign, non\u2010infectious, non\u2010inflammatory lesions of the central nervous system that are believed to originate from aberrant migration of ependymal cells during development. To our knowledge, this is the first report of an ependymal cyst in a non\u2010rodent veterinary species and the first report of a benign intracranial cyst of any classification in a non\u2010human primate.<\/jats:p>","DOI":"10.1111\/j.1600-0684.2008.00286.x","type":"journal-article","created":{"date-parts":[[2008,5,6]],"date-time":"2008-05-06T01:22:32Z","timestamp":1210036952000},"page":"239-244","source":"Crossref","is-referenced-by-count":10,"title":["Ependymal cyst in a cynomolgus macaque (<i>Macaca fascicularis<\/i>)"],"prefix":"10.1111","volume":"37","author":[{"given":"Ingrid L.","family":"Bergin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandy","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalen W","family":"Agnew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,9,23]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200005000-00041"},{"key":"e_1_2_6_3_2","first-page":"355","volume-title":"Benign Cystic Lesions in Tumors of the Central Nervous System in Atlas of Tumor Pathology","author":"Burger PC","year":"1994"},{"key":"e_1_2_6_4_2","first-page":"651","article-title":"Immunohistochemical study of intracranial cysts","volume":"8","author":"Coca S","year":"1993","journal-title":"Histol Histopathol"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-004-1097-x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.40.2.127"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00232774"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1789.2003.00526.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-006-0275-4"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(96)00228-5"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2007.00238.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2006.4.6.506"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1997.tb00835.x"}],"container-title":["Journal of Medical Primatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0684.2008.00286.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0684.2008.00286.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:03:11Z","timestamp":1698757391000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0684.2008.00286.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,23]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["10.1111\/j.1600-0684.2008.00286.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0684.2008.00286.x","archive":["Portico"],"relation":{},"ISSN":["0047-2565","1600-0684"],"issn-type":[{"value":"0047-2565","type":"print"},{"value":"1600-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,23]]}}}