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MRI revealed marked thickening of both optic nerves. Histopathological evaluation showed diffuse cellular infiltration at necropsy and a focus of SHIV\u2010infected cells. This is the first report of CNS pathology following chronic infection with an obligate R5 SHIV.<\/jats:p>","DOI":"10.1111\/j.1600-0684.2010.00416.x","type":"journal-article","created":{"date-parts":[[2010,4,13]],"date-time":"2010-04-13T02:20:48Z","timestamp":1271125248000},"page":"356-360","source":"Crossref","is-referenced-by-count":7,"title":["ORIGINAL ARTICLE: AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV\u20101157ipd3N4"],"prefix":"10.1111","volume":"39","author":[{"given":"Anapatricia","family":"Garc\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagadenahalli B.","family":"Siddappa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingsheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley T.","family":"Haase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Paul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawn","family":"Stroud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack A.","family":"Fountain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Villinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis J.","family":"Novembre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James G","family":"Else","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Evan Secor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth M.","family":"Ruprecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,9,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000265"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/13550280802132832"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/13550280802132857"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.84.5.546g"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-5-94"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02066-08"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2007.11.014"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00558-06"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328010beb5"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/13550280802074539"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5443.1353"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0306148"}],"container-title":["Journal of Medical Primatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0684.2010.00416.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0684.2010.00416.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T18:30:03Z","timestamp":1698949803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0684.2010.00416.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,2]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1111\/j.1600-0684.2010.00416.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0684.2010.00416.x","archive":["Portico"],"relation":{},"ISSN":["0047-2565","1600-0684"],"issn-type":[{"value":"0047-2565","type":"print"},{"value":"1600-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,2]]}}}