{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T18:27:05Z","timestamp":1784831225894,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T00:00:00Z","timestamp":1341532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold>Air sacculitis is an important clinical condition in non\u2010human primates.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold>We evaluated 37 baboons and seven chimpanzees with spontaneous air sacculitis submitted to pathology over a 20\u2010year period.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold>Air sacculitis was observed almost exclusively in males. Common reported signs were halitosis, coughing, nasal discharges, depression, anorexia, and weight loss. Gross lesions included thickened air sacs and suppurative exudate lining the walls. Microscopic lesions included marked epithelial hyperplasia or hypertrophy, necrosis, fibrosis, cellular infiltrates, and bacterial colonies. Mixed bacterial infections were more common than infections by single species of bacteria.<jats:italic>Streptococcus<\/jats:italic>sp. was the most frequent bacteria isolated in both baboons and chimpanzees.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold>This is the first report describing the gross and microscopic lesions of air sacculitis in chimpanzees. The preponderance of males suggests a male sex predilection in baboons.<\/jats:p>","DOI":"10.1111\/j.1600-0684.2012.00547.x","type":"journal-article","created":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T09:59:02Z","timestamp":1341568742000},"page":"266-277","source":"Crossref","is-referenced-by-count":27,"title":["Pathology of spontaneous air sacculitis in 37 baboons and seven chimpanzees and a brief review of the literature"],"prefix":"10.1111","volume":"41","author":[{"given":"Shyamesh","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Owston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gene B.","family":"Hubbard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Edward J.","family":"Dick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,6]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"Anonymous:Annual report: Cheyenne Mountain Zoological Park1963; 23."},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2010.00463.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02381391"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-012088661-6\/50018-1"},{"key":"e_1_2_6_6_2","doi-asserted-by":"crossref","first-page":"822","DOI":"10.2460\/javma.1980.177.09.822","article-title":"Fatal airsacculitis and pneumonia, with abortion, in an orangutan","volume":"177","author":"Cambre RC","year":"1980","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_7_2","first-page":"862","article-title":"Surgical drainage of a submandibular air sac in an orangutan","volume":"171","author":"Clifford DH","year":"1977","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_8_2","first-page":"433","article-title":"Laryngeal sacs in Orang\u2010outang (Pongo pygmaeus Hoppius)","volume":"9","author":"Giene J","year":"1965","journal-title":"Przglad Zoolgiczny"},{"key":"e_1_2_6_9_2","first-page":"610","article-title":"Klebsiella air sacculitis in the owl monkey (Aotus trivirgatus)","volume":"24","author":"Giles RC","year":"1974","journal-title":"Lab Anim Sci"},{"key":"e_1_2_6_10_2","first-page":"737","article-title":"Medical and surgical approach to laryngeal air sacculitis in a baboon caused by Pasteurella multocida","volume":"28","author":"Gross GS","year":"1978","journal-title":"Lab Anim Sci"},{"key":"e_1_2_6_11_2","unstructured":"GuilloudN McClureH:Air sac infection in the Orangutan (Pongo pygmaeus). 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