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The aim of the present study was to determine, by conventional indirect immunofluorescence, the nature and frequency of circulating antibodies to epithelial antigens in the sera of HCV\u2010positive patients who also have OLP. The study comprised four groups: 14 patients with OLP and HCV infection. 14 HCV\u2010seronegative patients with OLP, 21 HCV\u2010seropositive patients without OLP and 18 healthy controls. We found a significant association between the concomitance of OLP and HCV infection and the presence of such antibodies. It is concluded that some patients with HCV\u2010associated OLP may have circulating antibodies to epithelial antigens, although their precise aetiological role in the development of this disease in HCV infection remains unknown.<\/jats:p>","DOI":"10.1111\/j.1600-0714.1997.tb00007.x","type":"journal-article","created":{"date-parts":[[2006,4,30]],"date-time":"2006-04-30T04:31:38Z","timestamp":1146371498000},"page":"36-39","source":"Crossref","is-referenced-by-count":41,"title":["Antibodies to epithelial components in oral lichen planus (OLP) associated with hepatitis C virus (HCV) infection"],"prefix":"10.1111","volume":"26","author":[{"given":"G.","family":"Lodi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Piattelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"D'Amico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Artese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.R.","family":"Porter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,28]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)80376-3"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1001\/archderm.1994.01690010077011","article-title":"Lichen planus and hepatitits C virus\u2010related chronic active hepatitis","volume":"130","author":"Jubert C","year":"1994","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1994.tb03289.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247149"},{"key":"e_1_2_1_6_2","first-page":"547","article-title":"Lichen plan et hepatite virale C","volume":"121","author":"Benchikhi H.","year":"1994","journal-title":"Ann Dermatol Venereal"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90105-1"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0923-1811(92)90054-F"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1995.tb01966.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(05)80642-7"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1994.tb04962.x"},{"key":"e_1_2_1_12_2","first-page":"535","article-title":"Lichen planus after alpha\u2010interferon therapy for chronic hepatitis C","volume":"4","author":"Dupin N","year":"1994","journal-title":"Eur J Dermatol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)91029-H"},{"key":"e_1_2_1_14_2","first-page":"1051","article-title":"Lichen plan cutaneomuqueux induit par une deuxieme cure d'interfer\u2010on alpha a forte dose chez un malade atteint d'une hepatite virale C chronique","volume":"18","author":"Perreard M","year":"1994","journal-title":"Gastroenterol Clin Biol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247552"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(94)90312-3"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12876269"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(05)80072-1"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70027-F"},{"key":"e_1_2_1_20_2","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/hep.1840190407","article-title":"Immunological disorders in C virus chronic active hepatitis: a prospective case\u2010control study","volume":"19","author":"Pawlotsky JM","year":"1994","journal-title":"Hepatol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840210302"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(78)90383-3"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.1994.tb02852.x"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-8-199510150-00008"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1159\/000246315"}],"container-title":["Journal of Oral Pathology &amp; 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