{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:24:13Z","timestamp":1760549053972},"reference-count":64,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1672,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1111\/j.1600-0714.2010.01002.x","type":"journal-article","created":{"date-parts":[[2011,2,2]],"date-time":"2011-02-02T05:33:38Z","timestamp":1296624818000},"page":"593-597","source":"Crossref","is-referenced-by-count":26,"title":["Melatonin and cancer: current knowledge and its application to oral cavity tumours"],"prefix":"10.1111","volume":"40","author":[{"given":"Antonio","family":"Cutando","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Aneiros-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Aneiros-Cachaza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvador","family":"Arias-Santiago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,2]]},"reference":[{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/jez.1400230108","article-title":"Evidences associating pineal gland function with alterations in pigmentation","volume":"23","author":"McCord","year":"1917","journal-title":"J Exp Zool"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1016\/S0021-9258(18)69351-2","article-title":"Isolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glands","volume":"235","author":"Lerner","year":"1960","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/aja.1001620402","article-title":"The mammalian pineal gland: structure and function","volume":"162","author":"Reiter","year":"1981","journal-title":"Am J Anat"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.smrv.2004.08.001","article-title":"The basic physiology and pathophysiology of melatonin","volume":"9","author":"Claustrat","year":"2005","journal-title":"Sleep Med Rev"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"7447","DOI":"10.1016\/S0021-9258(18)47586-2","article-title":"A cholera toxin substrate regulates cyclic GMP content of rat pinealocytes","volume":"262","author":"Sugden","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1210\/edrv-12-2-151","article-title":"Pineal melatonin: cell biology of its synthesis and of its physiological interactions","volume":"12","author":"Reiter","year":"1991","journal-title":"Endocr Rev"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0006-8993(79)90848-5","article-title":"Pineal N-acetyltransferase and hydroxyindole-O-methyltransferase: control by the retinohypothalamic tract and the suprachiasmatic nucleus","volume":"174","author":"Klein","year":"1979","journal-title":"Brain Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"6405","DOI":"10.1523\/JNEUROSCI.21-16-06405.2001","article-title":"Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor","volume":"21","author":"Brainard","year":"2001","journal-title":"J Neurosci"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0166-4328(96)00083-6","article-title":"Neural control of the pineal gland","volume":"73","author":"Moore","year":"1996","journal-title":"Behav Brain Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S1521-690X(03)00016-2","article-title":"Melatonin: clinical relevance","volume":"17","author":"Reiter","year":"2003","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1600-079X.2008.00644.x","article-title":"Microtubules modulate melatonin receptors involved in phase-shifting circadian activity rhythms in vitro and in vivo evidence","volume":"46","author":"Jarzynka","year":"2009","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1124\/pr.55.2.2","article-title":"Generation of the melatonin endocrine message in mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides and other pineal transmitters","volume":"55","author":"Simonneaux","year":"2003","journal-title":"Pharmacol Rev"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1056\/NEJM200010123431510","article-title":"Melatonin, circadian rhythms and sleep","volume":"343","author":"Arendt","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1046\/j.1365-2826.2003.00989.x","article-title":"Role of melatonin in the regulation of human circadian rhythms and sleep","volume":"15","author":"Cajochen","year":"2003","journal-title":"J Neuroendocrinol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1095\/biolreprod.108.075655","article-title":"Melatonin and reproduction revisited","volume":"81","author":"Reiter","year":"2009","journal-title":"Biol Reprod"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1600-079X.2009.00701.x","article-title":"Kynuramines, metabolites of melatonin and others indoles: the resurrection of an almost forgotten class of biogenic amines","volume":"47","author":"Hardeland","year":"2009","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1034\/j.1600-079X.2003.02111.x","article-title":"Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin","volume":"34","author":"Tan","year":"2003","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-079X.1999.tb00597.x","article-title":"Physiological levels of melatonin contribute to the antioxidant capacity of human serum","volume":"27","author":"Benot","year":"1999","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1600-079X.2005.00304.x","article-title":"Protective effects of melatonin in experimental free radical-related ocular diseases","volume":"40","author":"Siu","year":"2006","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1600-079X.2005.00264.x","article-title":"Importance of the pineal gland, endogenous prostaglandins and sensory nerves in the gastroprotective actions of central and peripheral melatonin against stress-induced damage","volume":"39","author":"Brzozowski","year":"2005","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/10409230903044914","article-title":"Reducing oxidative\/nitrosative stress: a newly-discovered genre for melatonin","volume":"44","author":"Reiter","year":"2009","journal-title":"Cri Rev Biochem Mol Biol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1600-079X.1990.tb00692.x","article-title":"Correlation between salivary and serum melatonin: dependence on serum melatonin levels","volume":"9","author":"Laakso","year":"1990","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1006\/bbrc.1998.9826","article-title":"A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of melatonin interaction with hydroxyl radicals","volume":"253","author":"Tan","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1600-079X.1986.tb00760.x","article-title":"Human melatonin production decreases with age","volume":"3","author":"Sack","year":"1986","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1600-079X.2008.00580.x","article-title":"Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species","volume":"45","author":"Peyrot","year":"2008","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/(SICI)1097-4644(19970601)65:3<430::AID-JCB12>3.0.CO;2-J","article-title":"Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin","volume":"65","author":"Pozo","year":"1997","journal-title":"J Cell Biochem"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1034\/j.1600-079X.2000.290301.x","article-title":"Correlation between nuclear melatonin reception expression and enhanced cytokine production in human lymphocytic and monocytic cell lines","volume":"29","author":"Garcia-Maurino","year":"2000","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1385\/ENDO:27:2:101","article-title":"Functional MT1 and MT2 melatonin receptor in mammals","volume":"27","author":"Dubocovich","year":"2005","journal-title":"Endocrine"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB29|cit29","first-page":"57","article-title":"Melatonin: a potent, endogenous hydroxyl radical scavenger","volume":"1","author":"Tan","year":"1993","journal-title":"Endocr J"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/BF02253360","article-title":"Actions of melatonin in the reduction of oxidative stress: a review","volume":"7","author":"Reiter","year":"2000","journal-title":"J Biomed Sci"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/S0891-5849(99)00131-8","article-title":"Melatonin induces gamma-glutymlcysteine synthetase mediated by activator protei-1 in human vascular endothelial cells","volume":"27","author":"Urata","year":"1999","journal-title":"Free Radic Biol Med"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2174\/1568026023394443","article-title":"Chemical and physical properties and potential mechanisms: melatonin as a broad-spectrum antioxidant and free radical scavenger","volume":"2","author":"Tan","year":"2002","journal-title":"Curr Top Med Chem"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1034\/j.1600-079X.2001.300201.x","article-title":"Melatonin, mitochondria and cellular bioenergetics","volume":"30","author":"Acu\u00f1a-Castroviejo","year":"2001","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1600-079X.2007.00519.x","article-title":"Melatonin, endocrine pancreas and diabetes","volume":"44","author":"Peschke","year":"2008","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s007020050018","article-title":"An assessment of the antioxidant and antiamyloidogenic properties of melatonin: implications for Alzheimer\u2019s disease","volume":"107","author":"Pappolla","year":"2000","journal-title":"J Neural Transm"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB36|cit36","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0006-8993(02)02551-9","article-title":"Protective effect of melatonin in a chronic experimental model of Parkinson\u2019s disease","volume":"943","author":"Antolin","year":"2002","journal-title":"Brain Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1203\/00006450-200112000-00021","article-title":"Effects of melatonin treatment in septic newborns","volume":"50","author":"Gitto","year":"2001","journal-title":"Pediatr Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB38|cit38","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1034\/j.1600-079X.2001.310409.x","article-title":"Increased levels of malondialdehyde and nitrite\/nitrate in the blood of asphyxiated newborns: reduction by melatonin","volume":"31","author":"Fulia","year":"2001","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB39|cit39","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1007\/BF02505248","article-title":"Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5 methoxytryptamine). A dose response study","volume":"288","author":"Bangha","year":"1996","journal-title":"Arch Dermatol Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB40|cit40","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0272-6386(01)80124-4","article-title":"Melatonin prevents oxidative stress resulting from iron and erythropoietin administration","volume":"37","author":"Herrera","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB41|cit41","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1001\/archpsyc.58.11.1049","article-title":"Melatonin treatment for late dyskinesia: a double-blind, placebo-controlled, cross-over study","volume":"58","author":"Shamir","year":"2001","journal-title":"Arch Gen Psychiatry"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB42|cit42","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1211\/002235702760345374","article-title":"Melatonin: reducing the toxicity and increasing the efficacy of drugs","volume":"54","author":"Reiter","year":"2002","journal-title":"J Pharm Pharmacol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB43|cit43","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1902\/jop.2007.060244","article-title":"Local application of melatonin into alveolar sockets of beagle dogs reduces tooth removal-induced oxidative stress","volume":"78","author":"Cutando","year":"2007","journal-title":"J Periodontol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB44|cit44","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1600-079X.2004.00207.x","article-title":"Melatonin-estrogen interactions in breast cancer","volume":"38","author":"Sanchez-Barcelo","year":"2005","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB45|cit45","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0165-5728(98)00179-9","article-title":"Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells","volume":"92","author":"Garcia-Maurino","year":"1998","journal-title":"J Neuroimmunol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB46|cit46","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1600-079X.2005.00248.x","article-title":"A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes","volume":"39","author":"Tomas-Zapico","year":"2005","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB47|cit47","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.2741\/1089","article-title":"Molecular pharmacology, regulation and function of mammalian melatonin receptors","volume":"8","author":"Dubocovich","year":"2003","journal-title":"Front Biosci"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB48|cit48","first-page":"187","volume-title":"IUPHAR Compendium of Receptor Characterization and Classification","author":"Dubocovich","year":"1998"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB49|cit49","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1038\/bjp.2008.184","article-title":"Melatonin receptors, heterodimerization, signal transduction and binding sites: what\u2032s new?","volume":"154","author":"Jockers","year":"2008","journal-title":"Br J Pharmacol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB50|cit50","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0014-5793(96)00437-1","article-title":"Cloning of melatonin-related receptor from human pituitary","volume":"386","author":"Reppert","year":"1996","journal-title":"FEBS Lett"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB51|cit51","doi-asserted-by":"crossref","first-page":"E176","DOI":"10.1152\/ajpendo.00199.2007","article-title":"Altered metabolism in the melatonin-realted receptor(GPR50) knock out Mouse","volume":"294","author":"Ivanova","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB52|cit52","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1210\/endo-122-5-1825","article-title":"2[125]Iodomelatonin binding sites in hamster brain membranes: pharmacological characteristiques and regional distribution","volume":"122","author":"Duncan","year":"1998","journal-title":"Endocrinology"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB53|cit53","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1042\/BJ20071373","article-title":"Kinetic, thermodynamic and X-ray structural insights on the interaction of melatonin and analogs with quinone reductase","volume":"413","author":"Calamini","year":"2008","journal-title":"Biochem J"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB54|cit54","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.bcp.2005.09.030","article-title":"Characterization of melatoninergic MT3 binding site on the NRH: quinone oxidoreductasa 2 enzyme","volume":"71","author":"Mailliet","year":"2005","journal-title":"Biochem Pharmacol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB55|cit55","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1385\/ENDO:27:2:179","article-title":"Putting cancer to sleep at night: the neuroendocrine\/circadian melatonin signal","volume":"27","author":"Blask","year":"2005","journal-title":"Endocrine"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB56|cit56","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1158\/1055-9965.EPI-08-0605","article-title":"Melatonin as a biomarker of circadian dysregulation","volume":"17","author":"Mirick","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB57|cit57","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1034\/j.1600-079x.2002.1821.x","article-title":"Does melatonin induce apoptosis in MCF-7 human breast cancer cells in vitro?","volume":"32","author":"Cos","year":"2002","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB58|cit58","first-page":"97","article-title":"Circadian and sleep-dependent regulation of hormone release in humans","volume":"54","author":"Czeisler","year":"1999","journal-title":"Recent Prog Horm Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB59|cit59","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1007\/s10552-009-9405-0","article-title":"Total visual blindness is protective against breast cancer","volume":"20","author":"Flynn-Evans","year":"2009","journal-title":"Cancer Causes Control"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB60|cit60","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3109\/07420520903223984","article-title":"Is light-at-night a health risk factor or a health risk predictor?","volume":"26","author":"Kantermann","year":"2009","journal-title":"Chronobiol Int"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB61|cit61","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1111\/j.1600-079X.2008.00641.x","article-title":"Melatonin induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line","volume":"45","author":"Mart\u00edn-Renedo","year":"2008","journal-title":"J Pineal Res"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB62|cit62","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S1368-8375(00)00023-3","article-title":"Genetic aberrations in oral or head and neck squamous cell carcinoma 3: clinico-pathological applications","volume":"36","author":"Scully","year":"2000","journal-title":"Oral Oncol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB63|cit63","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S1470-2045(05)70540-4","article-title":"Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma","volume":"7","author":"Califano","year":"2006","journal-title":"Lancet Oncol"},{"key":"10.1111\/j.1600-0714.2010.01002.x-BIB64|cit64","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1111\/j.1349-7006.2008.00838.x","article-title":"Frequent silencing of a putative tumour suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous-cell carcinoma","volume":"99","author":"Nakamura","year":"2008","journal-title":"Cancer Sci"}],"container-title":["Journal of Oral Pathology &amp; Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0714.2010.01002.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1600-0714.2010.01002.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T18:42:30Z","timestamp":1712169750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0714.2010.01002.x"}},"subtitle":["Melatonin and oral cancer"],"short-title":[],"issued":{"date-parts":[[2011,2,2]]},"references-count":64,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011,9]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1600-0714.2010.01002.x","relation":{},"ISSN":["0904-2512"],"issn-type":[{"value":"0904-2512","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2,2]]}}}