{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:41:22Z","timestamp":1780443682801,"version":"3.54.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,8,29]],"date-time":"2011-08-29T00:00:00Z","timestamp":1314576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p><jats:italic>J Oral Pathol Med<\/jats:italic> (2012) <jats:bold>41<\/jats:bold>: 106\u2013112<\/jats:p><jats:p><jats:bold>Background:\u2002<\/jats:bold> Fine\u2010needle aspiration cytology (FNAC) is used as the main initial diagnostic investigation for lumps in the head and neck region. Major salivary glands and some minor salivary glands are easily accessible; therefore, they are optimal targets for FNAC. The aim of this study was to discuss the advantages and pitfalls of FNAC as compared to histopathology in the salivary gland lesions.<\/jats:p><jats:p><jats:bold>Material and methods:\u2002<\/jats:bold> A total of 127 FNAC were carried out on salivary gland lesions from January 2006 to December 2010 \u2013 a 5\u2010year period. Histopathological follow\u2010up data were obtained in 56 cases. The study was conducted to examine the sensitivity, specificity, and accuracy of FNAC for salivary gland swellings in comparison with histopathology.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The male\u2010to\u2010female ratio was 2.4:1. Parotid gland was involved in 51.1%, submandibular gland in 37%, sublingual gland in 4.7%, and minor salivary glands in 7% of patients. There were 55.9% cases of non\u2010neoplastic lesions and 44.1% cases of neoplastic lesions on biopsy. Sensitivity, specificity, positive predictive value, and negative predictive value of FNAC for malignant neoplastic lesions were 84.61%, 86.48%, 68.75%, and 94.11%, respectively, whereas for benign neoplastic lesions, they were 84.61%, 91.66%, 91.6%, and 85%, respectively.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Fine\u2010needle aspiration cytology is found to be a good sensitive and specific technique for the diagnosis of most of the salivary gland lesions. FNAC should be adopted as an initial investigation for all salivary gland swellings in conjunction with other investigations where appropriate.<\/jats:p>","DOI":"10.1111\/j.1600-0714.2011.01069.x","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T04:12:55Z","timestamp":1314850375000},"page":"106-112","source":"Crossref","is-referenced-by-count":66,"title":["Fine\u2010needle aspiration cytology: a reliable tool in the diagnosis of salivary gland lesions"],"prefix":"10.1111","volume":"41","author":[{"given":"Kanwar Deep","family":"Singh Nanda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,29]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880528"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197106)27:6<1415::AID-CNCR2820270622>3.0.CO;2-X"},{"key":"e_1_2_5_4_2","first-page":"281","article-title":"Aspiration cytology of salivary gland lesions advantages and pitfalls","volume":"37","author":"Kamal MM","year":"1994","journal-title":"Indian J Pathol Microbiol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.09.013"},{"key":"e_1_2_5_6_2","first-page":"314","article-title":"Correlation between fine needle aspiration biopsy and histologic findings in parotid masses. 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