{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T16:33:56Z","timestamp":1771518836501,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"vor","delay-in-days":9738,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[1981,2]]},"abstract":"<jats:p><jats:bold>Abstract\u2014<\/jats:bold> Forty\u2010four oral lesions with epithelial dysplasia and 25 other benign and malignant lesionsof the oarl mucosa were examined after ataining with hematoxylin\u2010eosin and diastase controlled PAS. The intensity of the PAS\u2010Positivity for glycogen, The grade of dysplasia, the type of keratinization and the degreeof subepithelial inflmmation were recored. Histologically normal epithelium at the margins of the lesions were used as controls. The presence and amount of glycogen in normal epithlium varied with the Form of keratinization in that non\u2010orparakeratinized epithelium was rich in glycogen where as there was a negative glycogen\u2010reaction in orthokeratinized epithelium. The most striking feature was and abrupt limitation of the glycogen at the junction between nondysplastic and dysplastic epithlium. The difference in the amount of glycogen in normal and dysplastic epithlium as assessed semiquantitativbely, was statistically significant. The diastase controlled PAS\u2010staining may therefore be a useful method of distinguishing dysplastic form nondysplastic epithlium in doubtjurl cases. Pseudoepitheliomatous hyperplastic epithelium covering granular cell myoblastoma did not contain any glycogen. Five of six squamous cell acrcinomas nand four verrucous carcinomas contained no demosstrable glycogen. Glycogen was present in the epithelium of the cases of lichen planus and \u201cdenture hyperplasia\u201d investigated.<\/jats:p>","DOI":"10.1111\/j.1600-0722.1981.tb01280.x","type":"journal-article","created":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T13:39:55Z","timestamp":1191245995000},"page":"79-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Content and distribution of glycogen in oral epithelial dysplasia"],"prefix":"10.1111","volume":"89","author":[{"given":"G\u00d6RAN","family":"ISACSSON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MERVYN","family":"SHEAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,10]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"43","article-title":"Glycogen in abonormal epithelium in rhe cervix","volume":"71","author":"Bo W.","year":"1961","journal-title":"Arch Pathol."},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/apm.1966.66.4.409"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/apm.1966.68.2.175"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(62)90382-1"},{"key":"e_1_2_1_6_2","first-page":"145","volume-title":"Theory and practice of histological techniques","author":"Cook L. 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