{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:33:04Z","timestamp":1780486384808,"version":"3.54.1"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,9,8]],"date-time":"2008-09-08T00:00:00Z","timestamp":1220832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:p>The aim of this study was to validate the use of digitized periapical radiographs in evaluating orthodontically induced apical root resorption against micro\u2010computed tomography (micro\u2010CT) scanning as a criterion standard test. In a standardized experimental protocol, 29 premolars in 16 subjects were tipped buccally for 8\u2003wk. Nineteen contralateral premolars not subjected to orthodontic movement served as controls. Standardized periapical radiographs were taken before and after the experimental period (Rx method). These teeth were extracted and scanned using a micro\u2010CT technique with a 9\u2003\u03bcm resolution. Two calibrated examiners assessed blindly the presence or absence of apical root resorption on digitized radiographs and three\u2010dimensional reconstructions of the scans. Significant differences were detected between the orthodontically moved teeth and controls: 86% of the orthodontically moved teeth and 21% of the control teeth showed apical root resorption when using micro\u2010CT as a validation method. A total of 55% of the experimental teeth and 5% of the control teeth showed resorption when assessed using Rx method. The Rx method showed a specificity of 78% and a sensitivity of 44%, which means that less than half of the cases with root resorption identified using a CT scanner were identified by radiography. Nearly all the orthodontically moved teeth showed apical root resorption. Apical root resorption may be underestimated when evaluated using digitized periapical radiographs.<\/jats:p>","DOI":"10.1111\/j.1600-0722.2008.00559.x","type":"journal-article","created":{"date-parts":[[2008,9,8]],"date-time":"2008-09-08T13:10:07Z","timestamp":1220879407000},"page":"467-472","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Diagnostic accuracy of digitized periapical radiographs validated against micro\u2010computed tomography scanning in evaluating orthodontically induced apical root resorption"],"prefix":"10.1111","volume":"116","author":[{"given":"Alexander","family":"Dudic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Giannopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Montet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Kiliaridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,9,8]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(82)90317-7"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/17.2.93"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(96)80015-1"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80383-0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjm047"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0889-5406(87)90455-0"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(97)70235-X"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/16.3.223"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/20.1.57"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4808931"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1987.tb00167.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(89)90276-4"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1992.tb00234.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.25.4.9084270"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.dmfr.4600626"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.113592"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/65487937"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/97564373"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.dmfr.4600313"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-5712(96)00026-7"},{"key":"e_1_2_6_22_2","first-page":"1","article-title":"Orthodontic tooth movement and root resorption with special reference to force magnitude and duration. 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