{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:10:33Z","timestamp":1773925833842,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T00:00:00Z","timestamp":1227225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J Oral Sciences"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:p>The aim of this study was to analyze whether generalized joint hypermobility (GJH) is a risk factor for temporomandibular disorders (TMD). We examined 895 subjects (20\u201360\u2003yr of age) in a population\u2010based cross\u2010sectional sample in Germany for GJH according to the Beighton classification and for TMD according to the Research Diagnostic Criteria for TMD (RDC\/TMD). After controlling for the effects of age, gender, and general joint diseases using multiple logistic regression analyses, hypermobile subjects (with four or more hypermobile joints on the 0\u20139 scale) had a higher risk for reproducible reciprocal clicking as an indicator for disk displacement with reduction (Odds Ratio (OR)\u2003=\u20031.68) compared with those subjects without hypermobile joints. Concurrently, subjects with four or more hypermobile joints had a lower risk for limited mouth opening (&lt;\u200335\u2003mm; OR\u2003= 0.26). The associations between GJH and reproducible reciprocal clicking or limited mouth opening were statistically significant in a trend test. No association was observed between hypermobility and myalgia\/arthralgia (RDC\/TMD Group I\/IIIa). In conclusion, GJH was found to be associated with non\u2010painful subtypes of TMD.<\/jats:p>","DOI":"10.1111\/j.1600-0722.2008.00581.x","type":"journal-article","created":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T09:56:01Z","timestamp":1227261361000},"page":"525-530","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Association between generalized joint hypermobility and signs and diagnoses of temporomandibular disorders"],"prefix":"10.1111","volume":"116","author":[{"given":"Christian","family":"Hirsch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike T.","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Stang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,11,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(83)90287-1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/18.3.167"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4805875"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-005-0620-z"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/154405910208100303"},{"key":"e_1_2_6_7_2","first-page":"47","article-title":"Generalized joint hypermobility and temporomandibular disorders: inherited connective tissue disease as a model with maximum expression","volume":"19","author":"De Coster PJ","year":"2005","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_8_2","first-page":"9","article-title":"Prevalence of different temporomandibular joint sounds, with emphasis on disc\u2010displacement, in patients with temporomandibular disorders and controls","volume":"26","author":"Elfving L","year":"2002","journal-title":"Swed Dent J"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-003-0434-9"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.32.5.413"},{"key":"e_1_2_6_11_2","first-page":"1777","article-title":"The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS)","volume":"27","author":"Grahame R","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.20376"},{"key":"e_1_2_6_13_2","first-page":"301","article-title":"Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique","volume":"6","author":"Dworkin SF","year":"1992","journal-title":"J Craniomandib Disord"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.51.6.793"},{"key":"e_1_2_6_15_2","first-page":"43","article-title":"Translating the research diagnostic criteria for temporomandibular disorders into German: evaluation of content and process","volume":"20","author":"John MT","year":"2006","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.07.018"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-007-0708-z"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/0471445428.ch18"},{"key":"e_1_2_6_19_2","first-page":"203","volume-title":"Case\u2010Control Studies","author":"Schlesselman JJ","year":"1982"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.51.1.87"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(92)90289-3"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.2000.00546.x"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116206"},{"key":"e_1_2_6_24_2","first-page":"143","article-title":"Problems of the use of the trend test as a dose\u2010response measurement in epidemiology","volume":"11","author":"Perez\u2010Hoyos S","year":"1997","journal-title":"Gac Sanit"},{"key":"e_1_2_6_25_2","first-page":"93","article-title":"The etiology of temporomandibular disorders: implications for treatment","volume":"15","author":"Green CS","year":"2001","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_26_2","first-page":"218","article-title":"Relationship between overbite\/overjet and clicking or crepitus of the temporomandibular joint","volume":"19","author":"Hirsch C","year":"2005","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_27_2","first-page":"163","article-title":"Clinical utility of mandibular movement ranges","volume":"7","author":"Szentpetery A","year":"1993","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/00220345990780031101"},{"key":"e_1_2_6_29_2","first-page":"101","article-title":"Studies on function and dysfunction of the masticatory system. II. Index for anamnestic and clinical dysfunction and occlusal state","volume":"67","author":"Helkimo M","year":"1974","journal-title":"Swed Dent J"},{"key":"e_1_2_6_30_2","first-page":"231","article-title":"A study of joint mobility in a normal population","volume":"28","author":"Seow CC","year":"1999","journal-title":"Ann Acad Med Singap"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/26.1.9"},{"key":"e_1_2_6_32_2","first-page":"240","article-title":"Comparing TMD diagnoses and clinical findings at Swedish and US TMD centres using research diagnostic criteria for temporomandibular disorders","volume":"10","author":"List T","year":"1996","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_33_2","first-page":"21","article-title":"Prevalence of temporomandibular disorder subtypes, psychologic distress, and psychosocial dysfunction in Asian patients","volume":"17","author":"Yap AU","year":"2003","journal-title":"J Orofac Pain"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.52.7.494"},{"key":"e_1_2_6_35_2","first-page":"1774","article-title":"Joint hypermobility and primary fibromyalgia: a clinical enigma","volume":"27","author":"Karaaslan Y","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_6_36_2","first-page":"59","volume-title":"Dritte Deutsche Mundgesundheitsstudie (DMS III)","author":"Micheelis W","year":"1999"},{"key":"e_1_2_6_37_2","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1742-1241.2000.tb11910.x","article-title":"Hypermobility \u2013 not a circus act","volume":"54","author":"Grahame R","year":"2000","journal-title":"Int J Clin Pract"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1177\/10454411970080030401"},{"key":"e_1_2_6_39_2","doi-asserted-by":"publisher","DOI":"10.3310\/hta7280"}],"container-title":["European Journal of Oral Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0722.2008.00581.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0722.2008.00581.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T23:11:42Z","timestamp":1696979502000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0722.2008.00581.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,21]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1111\/j.1600-0722.2008.00581.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0722.2008.00581.x","archive":["Portico"],"relation":{},"ISSN":["0909-8836","1600-0722"],"issn-type":[{"value":"0909-8836","type":"print"},{"value":"1600-0722","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,21]]},"assertion":[{"value":"2008-11-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}