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Our identification of 5\u2010<jats:italic>S<\/jats:italic>\u2010cysteinyldopa as the source of formaldehyde\u2010induced fluorescence of normal and pathological melanocytes started a series of investigations into this amino acid, enzymatic and non\u2010enzymatic oxidation of catecholic compounds and the metabolism of thiols. All melanocytes with functioning tyrosinase produce cysteinyldopas and the levels of 5\u2010<jats:italic>S<\/jats:italic>\u2010cysteinyldopa in serum and urine are related to the size and pigment forming activity of the melanocyte population. The determination of 5\u2010<jats:italic>S<\/jats:italic>\u2010cysteinyldopa in serum or urine is a sensitive diagnostic method in the detection of melanoma metastasis. Some non\u2010specific formation of cysteinyldopa is present in the body, as demonstrated by 5\u2010<jats:italic>S<\/jats:italic>\u2010cysteinyldopa in individuals with tyrosinase\u2010negative albinism.<\/jats:p>","DOI":"10.1111\/j.1600-0749.2003.00127.x","type":"journal-article","created":{"date-parts":[[2004,12,28]],"date-time":"2004-12-28T07:36:52Z","timestamp":1104219412000},"page":"191-202","source":"Crossref","is-referenced-by-count":2,"title":["The Pigmented Life of a Redhead"],"prefix":"10.1111","volume":"17","author":[{"given":"Hans","family":"Rorsman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,3,11]]},"reference":[{"key":"e_1_2_22_2_2","first-page":"193","volume-title":"Cutaneous Aging","author":"Rorsman H","year":"1988"},{"key":"e_1_2_22_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1195-328"},{"key":"e_1_2_22_4_2","volume-title":"L\u00e4kekonstens Historia. 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