{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:43:15Z","timestamp":1790264595966,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,3,11]],"date-time":"2004-03-11T00:00:00Z","timestamp":1078963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pigment Cell Research"],"published-print":{"date-parts":[[2004,4]]},"abstract":"<jats:p>As is the case with many other autoimmune diseases, there is an association between vitiligo and HLA complex. HLA subtypes vary with racial\/ethnic background. The purpose of this study was to determine which HLA class I antigens and HLA class II alleles are associated with Turkish vitiligo patients. Forty\u2010one patients with vitiligo and 61 healthy control subjects were typed for HLA class II alleles. Thirty\u2010three out of 41 patients with vitiligo and 100 healthy transplant donors were typed for HLA class I antigens. HLA DNA typing was performed by polymerase chain reaction\/sequence specific primer method for class II. HLA typing for class I was performed by serological method. The frequency of HLA DRB1*03 was 0.6340 in patients compared to 0.2950 in controls (P\u2003=\u20030.0014). The frequency of HLA DRB1*04 was found to be 0.6830 in patients compared to 0.2950 in controls (P\u2003=\u20030.00026). The allele HLA DRB1*07 was present in 0.390 of patients compared to 0.0820 of the controls (P\u2003=\u20030.0004). A preventive antigen for the manifestation of vitiligo has not been identified in this study. Our findings suggest that DRB1*03, DRB1*04 and DRB1*07 alleles are genetic markers for general susceptibility to vitiligo in a Turkish population.<\/jats:p>","DOI":"10.1111\/j.1600-0749.2004.00141.x","type":"journal-article","created":{"date-parts":[[2004,12,28]],"date-time":"2004-12-28T07:36:52Z","timestamp":1104219412000},"page":"181-184","source":"Crossref","is-referenced-by-count":49,"title":["Association of HLA Class I Antigens and HLA Class II Alleles with Vitiligo in a Turkish Population"],"prefix":"10.1111","volume":"17","author":[{"given":"Hal\u0130s B\u00fclent","family":"Ta\u015ftan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Akar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Funda Eli\u0307f","family":"Orkuno\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ercan","family":"Arca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali\u0307","family":"\u0130nal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,3,11]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70194-X"},{"key":"e_1_2_10_3_2","first-page":"757","article-title":"HLA class II antigen associations help to define two types of alopecia areata","volume":"33","author":"Colombe BW","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-313X.1995.tb00232.x"},{"key":"e_1_2_10_5_2","first-page":"23","article-title":"Vitiligo is associated with HLA\u2010A2 and HLA\u2010Dw7 in the Slovak population","volume":"42","author":"Buc M","year":"1996","journal-title":"Folia Biol (Praha)"},{"key":"e_1_2_10_6_2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1001\/archderm.1990.01670250062009","article-title":"Vitiligo is associated with HLA\u2010DR4 in black patients: a preliminary report","volume":"126","author":"Dunston GM","year":"1990","journal-title":"Arch Dermatol"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1991.tb02984.x"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)80279-5"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916939209035163"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000250480"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247426"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-2478(91)90245-6"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247240"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1155\/1993\/356874"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1995.tb01279.x"},{"key":"e_1_2_10_16_2","first-page":"13","article-title":"Occurrence rates of HLA\u2010DRB1, HLA\u2010DQB1 and HLA\u2010DPB1 alleles in patients suffering from vitiligo","volume":"8","author":"Buc M","year":"1998","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04288.x"},{"key":"e_1_2_10_18_2","first-page":"236","article-title":"HLA class II alleles in patients with alopecia areata","volume":"12","author":"Akar A","year":"2002","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12412584"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70394-6"}],"container-title":["Pigment Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0749.2004.00141.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0749.2004.00141.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T19:03:06Z","timestamp":1695841386000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0749.2004.00141.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,11]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["10.1111\/j.1600-0749.2004.00141.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0749.2004.00141.x","archive":["Portico"],"relation":{},"ISSN":["0893-5785","1600-0749"],"issn-type":[{"value":"0893-5785","type":"print"},{"value":"1600-0749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3,11]]}}}