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This article presents an efficacious, highly safe, minimally invasive, practical and low\u2010cost periodontal therapy that involves professional and patient\u2010administered mechanical therapy and antimicrobial agents. The major components are scaling for calculus removal, periodontal pocket irrigation with potent antiseptics, and treatment with systemic antibiotics for advanced disease. Povidone\u2010iodine and sodium hypochlorite have all the characteristics for becoming the first\u2010choice antiseptics in the management of periodontal diseases. Both agents show excellent antibacterial and antiviral properties, are readily available throughout the world, have been safely used in periodontal therapy for decades, offer significant benefits for individuals with very limited financial resources, and are well accepted by most dental professionals and patients. Four per cent chlorhexidine applied with a toothbrush to the most posterior part to the tongue dorsum can markedly reduce or eliminate halitosis in most individuals. Systemic antibiotics are used to treat periodontopathic bacteria that are not readily reached by topical therapy, such as pathogens within gingival tissue, within furcation defects, at the base of periodontal pockets, and on the tongue, tonsils and buccal mucosae. Valuable antibiotic therapies are amoxicillin\u2010metronidazole (250\u2003mg of amoxicillin and 250\u2003mg of metronidazole, three times daily for 8\u2003days) for young and middle\u2010aged patients, and ciprofloxacin\u2010metronidazole (500\u2003mg of each, twice daily for 8\u2003days) for elderly patients and for patients in developing countries who frequently harbor enteric rods subgingivally. Scaling to remove dental calculus and the prudent use of inexpensive antimicrobial agents can significantly retard or arrest progressive periodontitis in the great majority of patients.<\/jats:p>","DOI":"10.1111\/j.1600-0757.2011.00429.x","type":"journal-article","created":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T05:52:42Z","timestamp":1345614762000},"page":"110-137","source":"Crossref","is-referenced-by-count":104,"title":["Low\u2010cost periodontal 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