{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:03:32Z","timestamp":1787015012902,"version":"build-2736575974"},"reference-count":47,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T00:00:00Z","timestamp":1228953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:p>\n                    <jats:bold>Background and Objective:\u2002<\/jats:bold>\n                    The highest prevalence of Beh\u00e7et\u2019s disease (BD) has been reported in Turkey, and therefore research of relations between BD and other disorders have become important in the Turkish population. Since oral aphthous ulcers impair tooth brushing, reducing complaints about aphthous ulcers will motivate the patient to maintain better oral hygiene performance and will thus reduce plaque accumulation and periodontal scores. The purpose of this controlled case study was to evaluate the relationship between the severity of periodontal scores and Beh\u00e7et\u2019s disease, and to compare the treatment modalities with neodymium\u2010doped yttrium aluminium garnet (Nd:YAG) laser and medication on the recurrent aphthous ulcers in BD patients by considering the degree of pre\u2010 and post\u2010treatment pain, discomfort and functional complications.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Material and Methods:\u2002<\/jats:bold>\n                    The periodontal status of 28\u2003BD patients was evaluated according to periodontal indices. The BD patients were also assessed for clinical severity score as described previously. Levels of pre\u2010 and post\u2010treatment pain and functional complications were assessed at patient visits on days\u20031, 4 and 7.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:\u2002<\/jats:bold>\n                    Periodontal indices, the number of oral ulcers and the daily frequency of tooth brushing were related to the severity scores of BD (\n                    <jats:italic>p<\/jats:italic>\n                    \u2003&lt;\u20030.001). The results indicated that BD patients treated with the Nd:YAG laser had less post\u2010treatment pain and fewer functional complications and reported immediate relief of pain and faster healing (\n                    <jats:italic>p<\/jats:italic>\n                    \u2003&lt;\u20030.001).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:\u2002<\/jats:bold>\n                    Our results suggest that periodontal status is worse in BD patients and is associated with disease severity; also, the Nd:YAG laser has better patient acceptance, shorter treatment time and lower rates of pain and post\u2010treatment adverse events among BD patients with oral recurrent aphthous stomatitis.\n                  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