{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:29:42Z","timestamp":1793039382602,"version":"4.5.0"},"reference-count":72,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,5,11]],"date-time":"2005-05-11T00:00:00Z","timestamp":1115769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:p>The treatment of sclerosing skin diseases [systemic sclerosis, localized scleroderma, lichen sclerosus et atrophicus, sclerodermoid graft\u2010vs.\u2010host disease, scleredema adultorum (Buschke), scleromyxedema and necrobiosis lipoidica] is difficult and remains a great challenge. Numerous treatments, some with potentially hazardous side effects, are currently used with only limited success. The introduction of phototherapy and photochemotherapy for sclerosing skin diseases has considerably enriched the therapeutic panel and proven useful in a number of sclerosing skin diseases especially in localized scleroderma. Two phototherapeutic modalitites are used for the treatment of sclerosing skin diseases, long\u2010wave ultraviolet A and psoralen plus ultraviolet A (PUVA). This article reviews current knowledge about the application of phototherapy and photochemotherapy to various sclerosing skin disorders.<\/jats:p>","DOI":"10.1111\/j.1600-0781.2005.00154.x","type":"journal-article","created":{"date-parts":[[2005,5,11]],"date-time":"2005-05-11T08:35:28Z","timestamp":1115800528000},"page":"157-165","source":"Crossref","is-referenced-by-count":32,"title":["Phototherapy and photochemotherapy of sclerosing skin diseases"],"prefix":"10.1111","volume":"21","author":[{"given":"Michaela","family":"Brenner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Herzinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola","family":"Berking","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Plewig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Degitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,5,11]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92449-X"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91843-4"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)80277-0"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70533-X"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05261.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2000.d01-1.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1996.03890350138034"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1996.03890350138033"},{"key":"e_1_2_5_10_2","first-page":"100","article-title":"Phototesting in bath\u2010PUVA","volume":"12","author":"Schempp CM","year":"1996","journal-title":"marked reduction of 8-methoxypsoralen (8-MOP) activity within one hour after an 8-MOP bath"},{"key":"e_1_2_5_11_2","first-page":"991","article-title":"Kinetics and dose\u2010response of photosensitivity in cream psoralen plus ultraviolet A photochemotherapy","volume":"144","author":"Grundmann\u2010Kollmann M","year":"2001","journal-title":"comparative in vivo studies after topical application of three standard preparations"},{"key":"e_1_2_5_12_2","first-page":"22","article-title":"Guidelines for topical PUVA","volume":"142","author":"Halpern SM","year":"2000","journal-title":"a report of a workshop of the British photodermatology group"},{"key":"e_1_2_5_13_2","first-page":"2880","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"H\u00f6nigsmann H","year":"1999"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00700.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12522855"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.14.6666"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114576"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.5.595"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.124618"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000073093"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.117735"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2001.018003241.x"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2001.170401.x"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb14925.x"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70172-6"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1996.03890350014001"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2003.03016.x"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.105503"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.1998.tb00758.x"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70193-2"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.1.99"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.2.275"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.105165"},{"key":"e_1_2_5_34_2","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1001\/archderm.1997.03890480123023","article-title":"Psoralen bath plus UV\u2010A therapy. 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