{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:15:45Z","timestamp":1770977745380,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,9,11]],"date-time":"2008-09-11T00:00:00Z","timestamp":1221091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:p><jats:bold>Background: <\/jats:bold> The purpose of this study is to evaluate the efficacy and safety of 308\u2010nm monochromatic excimer light (MEL) in the treatment of psoriasis vulgaris and palmoplantar psoriasis.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> Thirty\u2010five patients with psoriasis vulgaris and 15 patients with palmoplantar psoriasis were recruited for this study. Thirty patients with psoriasis vulgaris completed a total of 16 treatments with 308\u2010nm MEL twice a week, and 15 patients palmoplantar psoriasis completed 25 treatments administered once weekly. The clinical response to therapy and adverse effects were recorded.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Patients with psoriasis vulgaris (<jats:italic>n<\/jats:italic>=30) showed a 74.6% improvement in the mean psoriasis area and severity index score after a total of 16 MEL treatments (2 \u00d7\/week) with 36.7% of the patients (<jats:italic>n<\/jats:italic>=11) achieving clearance. Patients with palmoplantar psoriasis (<jats:italic>n<\/jats:italic>=15) showed a 52.5% improvement in the mean severity index score after a total of 25 MEL treatments (1 \u00d7\/week) with only one patient (6.7%) achieving clearance. The MEL therapy was well tolerated with a low incidence of side effects, which included pruritus, erythema and blister formation.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> The 308\u2010nm MEL can be utilized as an effective and safe treatment modality for patients with mild\u2010to\u2010moderate psoriasis vulgaris and palmoplantar psoriasis.<\/jats:p>","DOI":"10.1111\/j.1600-0781.2008.00364.x","type":"journal-article","created":{"date-parts":[[2008,9,11]],"date-time":"2008-09-11T11:57:40Z","timestamp":1221134260000},"page":"231-236","source":"Crossref","is-referenced-by-count":26,"title":["Evaluation of 308\u2010nm monochromatic excimer light in the treatment of psoriasis vulgaris and palmoplantar psoriasis"],"prefix":"10.1111","volume":"24","author":[{"given":"Ling","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ally\u2010Khan","family":"Somani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei\u2010Hong","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi\u2010Zhong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,9,11]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"2880","volume-title":"Dermatology in general medicine","author":"Honigmann H","year":"1999"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2340\/00015555-0002","article-title":"Treatment of palmoplantar psoriasis with monochromatic excimer light (308\u2010nm) versus cream PUVA","volume":"86","author":"Neumann NJ","year":"2006","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1988.tb03489.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12479366"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2007.00317.x"},{"key":"e_1_2_6_7_2","first-page":"1376","article-title":"Wide\u2010area 308\u2010nm phototherapy with nonlaser light in the treatment of psoriasis","volume":"152","author":"Mavilia L","year":"2005","journal-title":"results of a pilot study"},{"key":"e_1_2_6_8_2","first-page":"99","article-title":"Evaluation of a novel 308\u2010nm monochromatic excimer light delivery system in dermatology","volume":"152","author":"Aubin F","year":"2005","journal-title":"a pilot study in different chronic localized dermatoses"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06533.x"},{"key":"e_1_2_6_10_2","first-page":"408","article-title":"Monochromatic excimer light (308 nm)","volume":"17","author":"Bianchi B","year":"2003","journal-title":"an immunohistochemical study of cutaneous T cells and apoptosis-related molecules in psoriasis"},{"key":"e_1_2_6_11_2","first-page":"1","article-title":"Paired comparison of bathwater versus oral delivery of 8\u2010methoxypsoralen in psoralen plus ultraviolet","volume":"22","author":"Hofer A","year":"2006","journal-title":"a therapy for chronic palmoplantar psoriasis"},{"key":"e_1_2_6_12_2","first-page":"11","article-title":"308 nm monochromatic excimer light for the treatment of palmoplantar psoriasis","volume":"13","author":"Campolmi P","year":"2002","journal-title":"Int J Immunopathol Pharmacol"},{"key":"e_1_2_6_13_2","first-page":"14","article-title":"308 nm monochromatic excimer light in psoriasis. Clinical evaluation and study of cytokine levels in the skin","volume":"13","author":"Cappugi P","year":"2002","journal-title":"Int J Immunopathol Pharmacol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01503.x"},{"key":"e_1_2_6_15_2","first-page":"1250","article-title":"Ultraviolet B 308\u2010nm excimer laser treatment of psoriasis","volume":"149","author":"Gerber W","year":"2003","journal-title":"a new phototherapeutic approach"},{"key":"e_1_2_6_16_2","first-page":"900","article-title":"Efficacy of the 308\u2010nm excimer laser for treatment of psoriasis","volume":"46","author":"Feldman SR","year":"2002","journal-title":"results of a multicenter study"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.09.014"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0781.2008.00364.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0781.2008.00364.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:55:28Z","timestamp":1697061328000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0781.2008.00364.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,11]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["10.1111\/j.1600-0781.2008.00364.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0781.2008.00364.x","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,11]]}}}