{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:13:08Z","timestamp":1791994388116,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T00:00:00Z","timestamp":1304380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p><jats:bold>Background: <\/jats:bold> Segmental vitiligo (SV), which frequently accompanies poliosis, indicating a poor prognosis that is likely resistant to treatments.<\/jats:p><jats:p><jats:bold>Objectives: <\/jats:bold> In this study, we performed a retrospective analysis to evaluate the treatment response to 308\u2003nm excimer laser in SV patients.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> A retrospective chart and photographic review was performed on 80 SV patients who had been treated with 308\u2003nm excimer laser for &gt;3 months.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Eighty patients with SV (mean age: 24.0 years \u00b1 15.3, males: 50%) were included in this study. The mean grade of repigmentation was 2.3 after 20.6 months of mean treatment duration; 23.8% of 80 patients showed grade 4, 20% showed grade 3, and 56.2% showed grade 1\u20132 repigmentation. However, none of them achieved complete repigmentation with excimer laser. The degree of repigmentation was positively correlated with treatment duration (<jats:italic>r<\/jats:italic>=0.315, <jats:italic>P<\/jats:italic>=0.004) and cumulative ultraviolet (UV) dosage (<jats:italic>r<\/jats:italic>=0.366, <jats:italic>P<\/jats:italic>=0.001), whereas it was negatively correlated with disease duration (<jats:italic>r<\/jats:italic>=\u22120.265, <jats:italic>P<\/jats:italic>=0.017).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> This study suggests that SV has a better repigmentation response when excimer laser is used at earlier stages of the disease and long\u2010term use and high cumulative UV energy of the excimer laser elicit better responses. Additional treatments like surgical procedures in addition to excimer laser should be considered for complete repigmentation.<\/jats:p>","DOI":"10.1111\/j.1600-0781.2011.00587.x","type":"journal-article","created":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T05:06:22Z","timestamp":1304399182000},"page":"147-151","source":"Crossref","is-referenced-by-count":43,"title":["The effect of 308\u2003nm excimer laser on segmental vitiligo: a retrospective study of 80 patients with segmental vitiligo"],"prefix":"10.1111","volume":"27","author":[{"given":"Jeong Eun","family":"Do","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Yong","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do\u2010Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010Kyung","family":"Hann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Ho","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,3]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"671","article-title":"Segmental vitiligo","volume":"35","author":"Hann SK","year":"1996","journal-title":"clinical findings in 208 patients"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04172.x"},{"key":"e_1_2_6_4_2","first-page":"500","article-title":"White hairs in segmental vitiligo are related to poor response to phototherapy","volume":"37","author":"Lee DY","year":"2010","journal-title":"demonstration with portable digital microscopy"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-148X.2008.00528.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2006.00222.x"},{"key":"e_1_2_6_7_2","first-page":"727","article-title":"Treatment of vitiligo with the 308\u2010nm excimer laser","volume":"46","author":"Spencer JM","year":"2002","journal-title":"a pilot study"},{"key":"e_1_2_6_8_2","first-page":"470","article-title":"Narrowband ultraviolet B phototherapy and 308\u2010nm excimer laser in the treatment of vitiligo","volume":"60","author":"Nicolaidou E","year":"2009","journal-title":"a review"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1011-1344(02)00280-4"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2004.01477.x"},{"key":"e_1_2_6_11_2","first-page":"240","article-title":"Preservation of melanoblasts of white hair follicles of segmental vitiligo lesions","volume":"25","author":"Song HJ","year":"2011","journal-title":"a preliminary study"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-148X.2010.00703.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.1999.tb00861.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1998.00557.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2000.41.2.209"},{"key":"e_1_2_6_16_2","first-page":"188","article-title":"308\u2010nm excimer lamp vs. 308\u2010nm excimer laser for treating vitiligo","volume":"163","author":"Le Duff F","year":"2010","journal-title":"a randomized study"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02151.x"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0781.2011.00587.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0781.2011.00587.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:04:14Z","timestamp":1698757454000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0781.2011.00587.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1111\/j.1600-0781.2011.00587.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0781.2011.00587.x","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,3]]}}}