{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T23:29:30Z","timestamp":1785713370560,"version":"3.56.0"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,9,27]],"date-time":"2011-09-27T00:00:00Z","timestamp":1317081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p><jats:bold>Background\/purpose: <\/jats:bold> The value of psoriatic plaques pretreatment with specific topical preparations in the setting of NB\u2010ultraviolet\u2010B (UVB) therapy is debatable. It may be clarified through a comparative assessment between crude coal tar and petrolatum as pretreatment candidates.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> A prospective study included 40 patients with plaque psoriasis undergoing NB\u2010UVB therapy. We compared among three treatment regimens: NB\u2010UVB alone (control group; <jats:italic>n<\/jats:italic>=20) as well as NB\u2010UVB preceded by crude coal tar 3% on one side and petrolatum on the other side (cases group I and II; <jats:italic>n<\/jats:italic>=20). Tar and petrolatum were topically applied thrice\/day the day before NB\u2010UVB exposure. Applications were removed using olive oil directly before NB\u2010UVB exposure. Regimens' frequency was thrice\/week and the clinical outcome was assessed, through both psoriasis area and severity index (PASI) and physician global assessment (PGA) scores, at baseline and 3 months later.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> There were significant (<jats:italic>P<\/jats:italic>&lt;0.01) decreases in both PASI and PGA scores in all the groups. In comparison with the controls, cases revealed significantly (<jats:italic>P<\/jats:italic>&lt;0.05) higher improvement percentages in both PASI and PGA scores for both tar and petrolatum. This influence, through the PGA score, was significantly (<jats:italic>P<\/jats:italic>&lt;0.05) in favor of petrolatum.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> The pretreatment of psoriatic plaques with either petrolatum or crude coal tar may enhance the therapeutic outcome of NB\u2010UVB, which appeared to favor petrolatum.<\/jats:p>","DOI":"10.1111\/j.1600-0781.2011.00602.x","type":"journal-article","created":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T05:14:39Z","timestamp":1317186879000},"page":"226-230","source":"Crossref","is-referenced-by-count":13,"title":["The influence of psoriatic plaques pretreatment with crude coal tar vs. petrolatum on the efficacy of narrow\u2010band ultraviolet B: a half\u2010vs.\u2010half intra\u2010individual double\u2010blinded comparative study"],"prefix":"10.1111","volume":"27","author":[{"given":"Marwa A.","family":"Abdallah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekramy Ahmed","family":"El\u2010Khateeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shereen H.","family":"Abdel\u2010Rahman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,9,27]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"436","article-title":"A. 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